The role of aryl hydrocarbon hydroxylase in skin tumor initiation by 7,12-dimethylbenz(a)anthracene and 1,2,5,6-dibenzanthracene using DNA binding and thymidine-3H incorporation into DNA as criteria.
作者信息
Bowden G T, Slaga T J, Shapas B G, Boutwell R K
出版信息
Cancer Res. 1974 Oct;34(10):2634-42.
PMID:4416467
Abstract
摘要
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The role of aryl hydrocarbon hydroxylase in skin tumor initiation by 7,12-dimethylbenz(a)anthracene and 1,2,5,6-dibenzanthracene using DNA binding and thymidine-3H incorporation into DNA as criteria.以DNA结合以及3H-胸腺嘧啶核苷掺入DNA为标准，研究芳烃羟化酶在7,12-二甲基苯并(a)蒽和1,2,5,6-二苯并蒽引发皮肤肿瘤中的作用。
Cancer Res. 1974 Oct;34(10):2634-42.
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Microsomal hydroxylases: induction and role in polycyclic hydrocarbon carcinogenesis and toxicity.微粒体羟化酶：在多环烃致癌作用和毒性中的诱导及作用
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Dibenz[a,c]anthracene: a potent inhibitor of skin-tumor initiation by 7,12-dimethylbenz[a]anthracene.二苯并[a,c]蒽：一种由7,12-二甲基苯并[a]蒽引发皮肤肿瘤的强效抑制剂。
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Aryl hydrocarbon hydroxylase and polycyclic hydrocarbon tumorigenesis: effect of the enzyme inhibitor 7,8-benzoflavone on tumorigenesis and macromolecule binding.芳基烃羟化酶与多环烃肿瘤发生：酶抑制剂7,8-苯并黄酮对肿瘤发生及大分子结合的影响
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