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给予苯并吡喃后犬实验性胰腺炎的淋巴与血液酶及病理改变

Lymph and blood enzymes and pathologic alterations in canine experimental pancreatitis after administration of benzo-pyrones.

作者信息

Bartos V, Kolc J, Vanĕcek R, Málek P

出版信息

Scand J Gastroenterol. 1979;14(3):343-7. doi: 10.3109/00365527909179894.

DOI:10.3109/00365527909179894
PMID:441682
Abstract

The effect of Venalot, a combination of two benzo-pyrones, on canine experimental acute pancreatitis was examined. Activities of lymph and blood plasma enzymes, thoracic duct lymph flow, and morphological changes of the pancreas were compared with those of a control group of dogs. The drug was found to enhance the removal of amylase and trypsin via lymph from the gland and to decrease the elevation of plasma amylase and lactate dehydrogenase. When administered simultaneously with the induction of pancreatitis, benzo-pyrones were effective in the reduction of pancreatic edema and necroses.

摘要

研究了由两种苯并吡喃组成的组合药物维纳洛(Venalot)对犬实验性急性胰腺炎的影响。将胰腺的淋巴和血浆酶活性、胸导管淋巴流量以及形态变化与对照组犬进行了比较。发现该药物可增强淀粉酶和胰蛋白酶经腺体淋巴的清除,并降低血浆淀粉酶和乳酸脱氢酶的升高。当与胰腺炎诱导同时给药时,苯并吡喃可有效减轻胰腺水肿和坏死。

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