King C E, Goldstein M J
Schizophr Bull. 1979;5(1):118-29. doi: 10.1093/schbul/5.1.118.
Therapist ratings of patients' achievement of objectives in psychotherapy were used to examine the impact of drugs on psychotherapy, to identify attributes of patients who achieve therapy objectives, and to assess the importance of the implementation of a crisis-oriented model of therapy. Patients were part of a project investigating the long-acting phenothiazine fluphenazine enanthate and crisis-oriented family therapy in a 6-week program of aftercare treatment for briefly hospitalized first admission acute schizophrenics. The 44 patients in this study were randomly assigned to the psychotherapy condition and to either a high or low dosage of phenothiazines. Therapist ratings of the achievement of therapy objectives were significantly related to independent ratings on two outcome measures, the Global Assessment Scale and the Brief Psychiatric Rating Scale (BPRS) factor Thought Disorder, at 6-month followup. Analyses of predictors of the achievement of therapy objectives revealed significant interactions between drug level and Venables and O'Connor ratings of paranoid symptomatology among good permorbid patients and between drug level and BPRS ratings of Hostility for the entire sample.
治疗师对患者在心理治疗中目标达成情况的评分,被用于检验药物对心理治疗的影响、识别达成治疗目标的患者特征,以及评估实施以危机为导向的治疗模式的重要性。患者是一个项目的一部分,该项目在一个为期6周的后续治疗计划中,研究长效吩噻嗪庚酸氟奋乃静和以危机为导向的家庭治疗,针对首次入院短期住院的急性精神分裂症患者。本研究中的44名患者被随机分配到心理治疗组以及高剂量或低剂量的吩噻嗪组。在6个月的随访中,治疗师对治疗目标达成情况的评分与两项结果测量的独立评分显著相关,这两项结果测量分别是总体评估量表和简明精神病评定量表(BPRS)中的思维障碍因子。对治疗目标达成情况的预测因素分析显示,在病情较好的共病患者中,药物水平与偏执症状的维纳布尔斯和奥康纳评分之间存在显著交互作用,在整个样本中,药物水平与敌意的BPRS评分之间也存在显著交互作用。