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氯碱工人的个体汞暴露及其与血液和尿液汞水平的关系。

Individual mercury exposure of chloralkali workers and its relation to blood and urinary mercury levels.

作者信息

Lindstedt G, Gottberg I, Holmgren B, Jonsson T, Karlsson G

出版信息

Scand J Work Environ Health. 1979 Mar;5(1):59-69. doi: 10.5271/sjweh.2665.

DOI:10.5271/sjweh.2665
PMID:441710
Abstract

On two occasions, chloralkali workers were investigated with regard to personal air mercury exposure, blood mercury and urinary mercury. The first investigation (13 workers, 2 weeks) was made at an exposure above the threshold limit value (64 microgram/m3, range 36--112), the second (16 workers, 8 weeks) at a lower exposure (23 microgram/m3, range 15--43). At the higher level of exposure, good correlations were found between air exposure and blood or urinary mercury for the group, but not for individuals. At the lower level, the correlations were less pronounced for the group. For individuals, the best correlation was found between mean air exposure during one week and blood mercury about half a week later. Other individuals, mainly the least exposed, showed no such correlation. Corresponding correlations were not found for urinary mercury. The urinary excretion rate was determined only for the last few hours of the workday, but the results agree with earlier investigations of 24-h excretion on a group basis. The threshold limit value for mercury in air (50 microgram/m3) corresponds to 150--175 nmol Hg/1 blood (= 30--35 microgram/1) for the group, with large individual variation.

摘要

曾有两次针对氯碱工人进行了个人空气汞暴露、血汞和尿汞方面的调查。第一次调查(13名工人,为期2周)时,暴露水平高于阈限值(64微克/立方米,范围为36 - 112),第二次(16名工人,为期8周)时暴露水平较低(23微克/立方米,范围为15 - 43)。在较高暴露水平下,该组人群的空气暴露与血汞或尿汞之间存在良好的相关性,但个体之间不存在这种相关性。在较低暴露水平下,该组人群的相关性不那么明显。对于个体而言,一周内的平均空气暴露与大约半周后的血汞之间存在最佳相关性。其他个体,主要是暴露最少的个体,未显示出这种相关性。尿汞方面未发现相应的相关性。仅在工作日的最后几个小时测定了尿排泄率,但结果与早期对一组人群24小时排泄情况的调查结果一致。空气中汞的阈限值(50微克/立方米)对于该组人群相当于血汞150 - 175纳摩尔/升(= 30 - 35微克/升),个体差异较大。

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