Stepanov Iu B
Zh Mikrobiol Epidemiol Immunobiol. 1979 Apr(4):25-30.
The dynamics of natural resistance factors (complement, lysozyme, the bactericidal potency of blood serum) were found to be similar in rabbits with the toxic lesions of the liver resulting from the administration of carbon tetrachloride and in intact homologous rescipients receiving the serum of poisoned animals. Simultaneously a decrease in the complement titre and an increase in lysozyme activity and in the bactericidal potency of blood serum were observed. The effect thus revealed could be suppressed by treating the serum with contrical, a polyvalent proteinase inhibitor.
结果发现，给兔子注射四氯化碳造成肝脏中毒性损伤后，其天然抵抗因子（补体、溶菌酶、血清杀菌力）的动态变化，与接受中毒动物血清的同种健康受体相似。同时还观察到补体滴度降低，溶菌酶活性及血清杀菌力增强。用多价蛋白酶抑制剂抑肽酶处理血清后，所显示的这种作用可被抑制。
