三环类抗抑郁药丙咪嗪X射线结构的潜在药理学及理论意义 - Suppr | 超能文献

Possible pharmacological and theoretical implications of x-ray structure of the tricyclic antidepressant imipramine.

作者信息

Post M L, Kennard O, Horn A S

出版信息

Nature. 1974 Dec 6;252(5483):493-5. doi: 10.1038/252493a0.

DOI:10.1038/252493a0

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Possible pharmacological and theoretical implications of x-ray structure of the tricyclic antidepressant imipramine.三环类抗抑郁药丙咪嗪X射线结构的潜在药理学及理论意义

Nature. 1974 Dec 6;252(5483):493-5. doi: 10.1038/252493a0.

2

Theoretical studies on tricyclic antidepressants. I. Molecular structures.三环类抗抑郁药的理论研究。I. 分子结构。

Physiol Chem Phys. 1980;12(4):323-36.

3

EPR studies on the mechanism of biotransformation of tricyclic neuroleptics and antidepressants.三环类抗精神病药和抗抑郁药生物转化机制的电子顺磁共振研究

Adv Biochem Psychopharmacol. 1974;9(0):5-13.

4

X-ray structure of 3',5'-diacetyl-2'-deoxy-2'-fluorouridine: a pyrimidine nucleoside in the syn conformation.3',5'-二乙酰基-2'-脱氧-2'-氟尿苷的X射线结构：一种处于顺式构象的嘧啶核苷。

Biochim Biophys Acta. 1974 Sep 13;361(3):257-65. doi: 10.1016/0005-2787(74)90369-4.

5

Synthetic strategies to lower affinity for CYP2D6.降低对CYP2D6亲和力的合成策略。

Eur J Drug Metab Pharmacokinet. 1997 Oct-Dec;22(4):291-4. doi: 10.1007/BF03190959.

6

X-ray analytical reexamination of correlation of nitrogen lone-pair orientation with analgetic activity.氮孤对取向与镇痛活性相关性的X射线分析复验

J Med Chem. 1978 Feb;21(2):153-4. doi: 10.1021/jm00200a001.

7

Comparative in vitro and in vivo studies on the effects of tricyclic antidepressants on myocardial contractility.三环类抗抑郁药对心肌收缩力影响的体外与体内比较研究。

Recent Adv Stud Cardiac Struct Metab. 1975;10:59-69.

8

Blockade of heart 3H-norepinephrine up-take by 4-phenyl-1-aminotetralines: implications for the active conformation of imipramine-like drugs.4-苯基-1-氨基四氢萘对心脏3H-去甲肾上腺素摄取的阻断作用：对丙咪嗪类药物活性构象的影响

J Pharmacol Exp Ther. 1974 Dec;191(3):393-402.

9

Cyclizing compounds. V. Tertiary haloalkylamine derivatives related to the tricyclic psychopharmacological agents promazine, imipramine and amitriptyline.

Acta Pharm Suec. 1984;21(1):31-42.

10

Studies on the conformation and dynamics of the C8-substituted guanine adduct of the carcinogen acetylaminofluorene; model for a possible Z-DNA modified structure.致癌物乙酰氨基芴的C8-取代鸟嘌呤加合物的构象与动力学研究；一种可能的Z-DNA修饰结构模型。

Nucleic Acids Res. 1984 Nov 12;12(21):8219-33. doi: 10.1093/nar/12.21.8219.

引用本文的文献

1

Saffron: A potential drug-supplement for severe acute respiratory syndrome coronavirus (COVID) management.藏红花：一种用于严重急性呼吸综合征冠状病毒（COVID）治疗的潜在药物补充剂。

Heliyon. 2021 May;7(5):e07068. doi: 10.1016/j.heliyon.2021.e07068. Epub 2021 May 14.

2

Synthesis and some pharmacological properties of a conformationally restricted imipramine analogue.一种构象受限的丙咪嗪类似物的合成及某些药理性质

Pharm Weekbl Sci. 1983 Dec 16;5(6):329-32. doi: 10.1007/BF02074864.