Aplin C E, Brouhard B H, Cunningham R J, Richardson C J
Am J Dis Child. 1979 Jun;133(6):625-7. doi: 10.1001/archpedi.1979.02130060065014.
Plasma immunoreactive prostaglandin A (iPGA) values were determined for 14 premature infants before and after 48 hours of phototherapy and in a control group of six age-matched premature infants. At 4 to 8 days of life, the infants who had received phototherapy for 48 hours had significantly lower iPGA values compared with controls. At 2 to 3 days of life, four infants with a clinically apparent patent ductus arteriosus were found to have significantly elevated iPGA values compared with controls. After 48 hours of phototherapy, these infants likewise had a significant decrease in iPGA values compared with controls; in all four infants, the ductus closed spontaneously. Phototherapy is an effective method for decreasing plasma iPGA values in premature infants.
测定了14名早产儿在光疗48小时前后以及6名年龄匹配的早产对照组婴儿的血浆免疫反应性前列腺素A(iPGA)值。在出生4至8天时,接受48小时光疗的婴儿的iPGA值明显低于对照组。在出生2至3天时,发现4名临床上明显患有动脉导管未闭的婴儿的iPGA值明显高于对照组。经过48小时光疗后,这些婴儿的iPGA值与对照组相比同样显著下降;在所有4名婴儿中,动脉导管均自行闭合。光疗是降低早产儿血浆iPGA值的有效方法。