Selle H F, Holmes D W, Ingbar M L
Am J Public Health. 1979 Jun;69(6):574-80. doi: 10.2105/ajph.69.6.574.
A predicted shift in composition of the child-bearing population of the United States to higher maternal ages by year 2000 indicates that the number of chromosomally abnormal offspring of women age 35 and over will increase by 64% while the total number of women increases only 21%. We formulated a conceptual model of a health care system that predicts demand for amniocentesis from prospective patients in any particular region, the number of defective offspring detected, and the future cost of custodial care using any given level of detection effort. It was found that as capacity of clinic facilities and use by women age 35 and over in the area increased, the expenditure for amniocentesis combined with the cost of custodial care for undetected offspring decreased, assuming termination of affected pregnancies. Use of this model will enable health care managers to anticipate need for facilities, and also guide the formulation of social policy in the provision of new health services by enabling them to take into account the predictable effects of these services upon other public services.
预计到2000年,美国育龄人口的构成将向高龄产妇转移,这表明35岁及以上女性的染色体异常后代数量将增加64%,而女性总数仅增加21%。我们构建了一个医疗保健系统的概念模型,该模型可以预测任何特定地区潜在患者对羊膜穿刺术的需求、检测出的有缺陷后代数量,以及使用任何给定检测力度时未来监护护理的成本。研究发现,随着该地区诊所设施的容量以及35岁及以上女性对其使用的增加,假设终止受影响的妊娠,羊膜穿刺术的支出加上未检测出后代的监护护理成本会降低。使用该模型将使医疗保健管理人员能够预测对设施的需求,还能通过使他们考虑这些服务对其他公共服务的可预测影响,来指导制定提供新医疗服务的社会政策。