Povey R C
Infect Immun. 1974 Dec;10(6):1307-14. doi: 10.1128/iai.10.6.1307-1314.1974.
A total of 46 strains of feline calicivirus isolates from the United Kingdom, United States, Australia, and New Zealand were used in an investigation of their serological relationships based on the serum neutralization test. Although demonstrable antigenic variation exists between these isolates, it is shown that significant in vitro cross-activity exists between all these isolates to greater or lesser extent. All isolates tested may be regarded as serological variants of a single serotype of feline calicivirus. It is postulated that this relationship would provide for considerable cross-protection during successive exposures of cats to various feline caliciviruses.
基于血清中和试验,对来自英国、美国、澳大利亚和新西兰的总共46株猫杯状病毒分离株进行了血清学关系研究。尽管这些分离株之间存在明显的抗原变异,但结果表明,所有这些分离株之间在不同程度上均存在显著的体外交叉活性。所有测试的分离株都可被视为猫杯状病毒单一血清型的血清学变异株。据推测,这种关系在猫连续接触各种猫杯状病毒时可提供相当程度的交叉保护。