Keenan D M
Aust Vet J. 1979 Feb;55(2):54-7. doi: 10.1111/j.1751-0813.1979.tb15159.x.
Changes in concentration of a number of blood metabolites in 30 thoroughbred horses were recorded after an 1110 metre race. No significant changes occurred in blood urea or aspartate aminotransferase during the three hours after racing. Plasma sodium, potassium and calcium levels were increased immediately after racing but had returned to normal one hour after racing. Plasma phosphate showed a significant fall in concentration one hour after racing. Creatinine and lactic acid concentrations were elevated ten minutes after racing and although they subsequently decreased, the level of lactic acid was still significant one hour later. Uric acid levels were well above resting levels at ten minutes after racing but rose even more in the subsequent hour. Urinary uric acid levels were also elevated during this time. Three hours after racing some horses still had elevated plasma uric acid levels and all of them showed a significant rise in creatine phosphokinase. The possible physiological basis of these findings is discussed.
在1110米比赛后，记录了30匹纯种马体内多种血液代谢物浓度的变化。比赛后三小时内，血尿素或天冬氨酸转氨酶没有显著变化。比赛后血浆钠、钾和钙水平立即升高，但在比赛后一小时恢复正常。比赛后一小时血浆磷酸盐浓度显著下降。比赛后十分钟肌酐和乳酸浓度升高，尽管随后有所下降，但一小时后乳酸水平仍显著升高。比赛后十分钟尿酸水平远高于静息水平，但在随后一小时内升得更高。在此期间尿尿酸水平也升高。比赛后三小时，一些马的血浆尿酸水平仍然升高，并且它们所有的肌酸磷酸激酶都显著升高。讨论了这些发现可能的生理基础。
