Bos Astrid, Compagnie Ellen, Lindner Arno
Dierenkliniek Emmeloord, Emmeloord, The Netherlands.
Arbeitsgruppe Pferd, Jülich, Germany.
Vet Clin Pathol. 2018 Dec;47(4):625-628. doi: 10.1111/vcp.12666. Epub 2018 Nov 13.
Blood is collected for hematologic and biochemical analyses when racehorses perform poorly. However, racing affects most analyte levels; therefore, the timing of blood sampling can affect analyte levels and interpretations.
This study aimed to determine if the blood variable levels returned to pre-racing levels 2 and 3 days post-racing.
Blood was sampled from 17 healthy racehorses pre- and post-racing. The variables measured from plasma were albumin, cholesterol, creatinine, calcium (Ca), phosphorus (P), magnesium (Mg), sodium (Na), potassium (K), creatine phosphokinase (CK), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), gamma-glutamyl transferase (GGT), and cortisol. Hematocrit (HCT), hemoglobin (HGB), white blood cell (WBC), red blood cell (RBC), granulocyte, and lymphocyte counts were analyzed from blood collected in EDTA-coated vials.
Calcium was lower 3 days post-racing compared with 2 days pre-racing (P < 0.01), P and GGT were higher 2 and 3 days post-racing compared with those at the pre-racing timepoints (P ≤ 0.01), and RBC, HCT, and HGB were higher 2 days post-racing compared with those at the pre-racing and 3-day post-racing time points (P < 0.01, all).
A few blood biochemical and hematologic variables were significantly altered 2 and 3 days post-racing. The level of these changes did not affect the clinicopathologic interpretation of the values.
当赛马表现不佳时会采集血液进行血液学和生化分析。然而,比赛会影响大多数分析物水平;因此,采血时间会影响分析物水平及解读结果。
本研究旨在确定血液变量水平在赛后2天和3天是否恢复到赛前水平。
对17匹健康赛马在赛前和赛后进行采血。检测血浆中的变量包括白蛋白、胆固醇、肌酐、钙(Ca)、磷(P)、镁(Mg)、钠(Na)、钾(K)、肌酸磷酸激酶(CK)、天冬氨酸转氨酶(AST)、乳酸脱氢酶(LDH)、γ-谷氨酰转移酶(GGT)和皮质醇。对采集于乙二胺四乙酸(EDTA)抗凝管中的血液分析血细胞比容(HCT)、血红蛋白(HGB)、白细胞(WBC)、红细胞(RBC)、粒细胞和淋巴细胞计数。
与赛前2天相比,赛后3天钙水平降低(P < 0.01);与赛前时间点相比,赛后2天和3天P和GGT升高(P≤0.01);与赛前和赛后3天时间点相比,赛后2天RBC、HCT和HGB升高(均为P < 0.01)。
赛后2天和3天一些血液生化和血液学变量发生显著改变。这些变化的程度不影响这些数值的临床病理解读。