Rand C G, Jackson R J, Mackie C C
Can Med Assoc J. 1974 Dec 21;111(12):1312-4.
A diabetic survey was conducted among 4048 subjects well enough to report for work, using a questionnaire covering past, present, family and obstetric history, and a capillary blood glucose determination at least 1(1/2) hours after eating. A "positive screen" was obtained in 267 individuals, in 67 on the basis of elevated blood glucose value alone, in 179 on the basis of questionnaire responses alone, and in 21 by both criteria. Glucose tolerance tests were performed on 130 subjects (49% of eligible individuals) and yielded diabetic curves in 18, 6 and 33% respectively for the three categories of positive screening tests.It is suggested that the magnitude of the group with positive history only is such that future natural history studies must take this subsample into consideration.
对4048名身体状况良好、足以报到上班的受试者进行了糖尿病调查，采用一份涵盖既往史、现病史、家族史和产科史的问卷，并在进食至少1.5小时后测定毛细血管血糖。267人筛查呈“阳性”，其中67人仅基于血糖值升高，179人仅基于问卷回答，21人基于两项标准均呈阳性。对130名受试者（占符合条件个体的49%）进行了葡萄糖耐量试验，对于三类阳性筛查试验，分别有18%、6%和33%的受试者出现糖尿病曲线。有人提出，仅病史呈阳性的人群规模如此之大，以至于未来的自然史研究必须考虑到这个子样本。
