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[特殊接触对平滑肌和心肌组织兴奋传播过程中纤维相互作用的影响]

[Effect of specialized contacts on fiber interaction during the spread of excitation in smooth muscle and myocardial tissues].

作者信息

Pertsov A M, Medvinskiĭ A B

出版信息

Biofizika. 1979 Mar-Apr;24(2):293-8.

PMID:444610
Abstract

A mathematical model of closely packed parallel muscle fibres with side by side junctions was studied. High coupling coefficient for both heart and smooth muscle fibres was shown to be available at rather low junction permeability. The coupling coefficient for heart fibers is equal to 0.5 at specific junction membrane resistance as high as 100 omega cm2. For the same coupling ratio in smooth muscle the specific junction membrane resistance should be even greater (1000 omega cm2). The role of nexuses and tight junctions in conduction of excitation is discussed.

摘要

研究了具有并排连接的紧密排列平行肌纤维的数学模型。结果表明,对于心脏和平滑肌纤维,在相当低的连接通透性下即可获得高耦合系数。在特定连接膜电阻高达100Ω·cm²时,心脏纤维的耦合系数等于0.5。对于平滑肌中相同的耦合比,特定连接膜电阻应更大(1000Ω·cm²)。文中讨论了连接子和紧密连接在兴奋传导中的作用。

相似文献

1
[Effect of specialized contacts on fiber interaction during the spread of excitation in smooth muscle and myocardial tissues].[特殊接触对平滑肌和心肌组织兴奋传播过程中纤维相互作用的影响]
Biofizika. 1979 Mar-Apr;24(2):293-8.
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