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[无高度通透细胞接触的细胞中的电偶联]

[Electric coupling in cells without highly permeable cell contacts].

作者信息

Pertsov A M, Medvinskiĭ A B

出版信息

Biofizika. 1976 Jul-Aug;21(4):698-70.

PMID:1009155
Abstract

A mathematical model of two contacting cells is studied. Simple analytical formula are obtained which connect the transmission coefficient k with the parameters of contact zone (dimension of the contact region, resistence of the contact membrane, specific resistence of the interslit medium, width of intercellular slit) and with geometry of contacting cells. It is shown that in the absence of conductivity increase in the contact zone the values of transmission coefficient. k = 0.2 divided by 0.3. are available. k is evaluated for early embryonic cells. The mechanisms of electric coupling in early embryonic cells and in heart tissue are discussed.

摘要

研究了两个接触细胞的数学模型。得到了简单的解析公式,该公式将传输系数k与接触区的参数(接触区域的尺寸、接触膜的电阻、细胞间隙介质的比电阻、细胞间间隙的宽度)以及接触细胞的几何形状联系起来。结果表明,在接触区电导率没有增加的情况下,传输系数的值在0.2到0.3之间。对早期胚胎细胞的k值进行了评估。讨论了早期胚胎细胞和心脏组织中的电耦合机制。

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