小鼠脑室内直接注射的一些缺点。
Some shortcomings of direct intraventricular injection in mice.
作者信息
Shaw G G
出版信息
Br J Pharmacol. 1974 Apr;50(4):603-5. doi: 10.1111/j.1476-5381.1974.tb08596.x.
Abstract
The use of X-ray photography following injection of iophendylate to verify that intraventricular injections in mice have been satisfactorily accomplished is misleading since it fails to detect leakage into the periphery. Radioactive labelling reveals that a substantial proportion of the injected material is rapidly carried to the periphery in the bloodstream.
摘要
注射碘苯酯后使用X射线摄影来验证小鼠脑室内注射是否成功完成是有误导性的，因为它无法检测到注射物质渗漏到外周。放射性标记显示，相当一部分注射物质会在血液中迅速被带到外周。
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