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占据圆形栖息地的种群的遗传结构。

Genetic structure of a population occupying a circular habitat.

作者信息

Nagylaki T

出版信息

Genetics. 1974 Oct;78(2):777-90. doi: 10.1093/genetics/78.2.777.

DOI:10.1093/genetics/78.2.777
PMID:4448365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213234/
Abstract

The geographical structure of a finite population distributed continuously and homogeneously along a circular habit is explored. Selection is supposed to be absent, and the analysis is restricted to a single locus with discrete, non-overlapping generations. Assuming every mutant is new to the population, the rate of decay of genetic variability is obtained, and the probability that two homologous genes separated by a given distance are different alleles is calculated. If moments of the migration function higher than second are neglected, the eigenvalue equation is shown to be a simple trigonometric one, and the Fourier series giving the transient and stationary probabilities of allelism are summed in terms of elementary functions. The proportion of homozygotes, the effective number of alleles maintained in the population, and the amount of local differentiation of gene frequencies are discussed.

摘要

研究了在圆形栖息地连续且均匀分布的有限种群的地理结构。假定不存在选择,并且分析仅限于具有离散、非重叠世代的单个基因座。假设每个突变体对于种群来说都是新的,得出了遗传变异性的衰减率,并计算了被给定距离隔开的两个同源基因是不同等位基因的概率。如果忽略迁移函数高于二阶的矩,则特征值方程显示为一个简单的三角方程,并且给出等位基因瞬时和稳态概率的傅里叶级数用初等函数进行了求和。讨论了纯合子的比例、种群中维持的等位基因有效数量以及基因频率的局部分化量。

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1
Genetic structure of a population occupying a circular habitat.占据圆形栖息地的种群的遗传结构。
Genetics. 1974 Oct;78(2):777-90. doi: 10.1093/genetics/78.2.777.
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The coalescent in a continuous, finite, linear population.连续、有限、线性种群中的溯祖过程。
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Decay of genetic variability in geographically structured populations.地理结构种群中遗传变异性的衰减。
Proc Natl Acad Sci U S A. 1977 Jun;74(6):2523-5. doi: 10.1073/pnas.74.6.2523.

本文引用的文献

1
THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION.有限种群中能够维持的等位基因数量。
Genetics. 1964 Apr;49(4):725-38. doi: 10.1093/genetics/49.4.725.
2
The number of neutral alleles maintained in a finite, geographically structured population.在一个有限的、具有地理结构的群体中维持的中性等位基因的数量。
Theor Popul Biol. 1971 Dec;2(4):437-53. doi: 10.1016/0040-5809(71)90033-5.