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一名长期接受复方新诺明治疗的患者出现短暂性红细胞生成减少。

Transient erythroid hypoplasia in a patient on long-term co-trimoxazole therapy.

作者信息

Stephens M E

出版信息

Postgrad Med J. 1974 Apr;50(582):235-7. doi: 10.1136/pgmj.50.582.235.

DOI:10.1136/pgmj.50.582.235
PMID:4449776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2495564/
Abstract

The occurrence of isolated erythroid hypoplasia in a patient on long-term treatment with co-trimoxazole is described. It is suggested that this haematological complication, which has not been previously reported, was due to hypersensitivity to the sulphonamide component.

摘要

本文描述了一名长期接受复方新诺明治疗的患者出现单纯红细胞生成低下的情况。据推测，这种此前未被报道过的血液学并发症是由对磺胺类成分过敏所致。

相似文献

1
Transient erythroid hypoplasia in a patient on long-term co-trimoxazole therapy.一名长期接受复方新诺明治疗的患者出现短暂性红细胞生成减少。
Postgrad Med J. 1974 Apr;50(582):235-7. doi: 10.1136/pgmj.50.582.235.
2
Pancytopenia in an infant associated with sulfamethoxazole-trimethoprim therapy.
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Toxicity of co-trimoxazole in nutritional haematinic deficiency.复方新诺明在营养性造血素缺乏中的毒性。
Postgrad Med J. 1973 Aug;49(574):596-8. doi: 10.1136/pgmj.49.574.596.
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Clinical experience with adverse reactions to trimethoprim-sulfamethoxazole.
J Infect Dis. 1973 Nov;128:Suppl:607-12 p. doi: 10.1093/infdis/128.supplement_3.s607.
5
[Pure red-cell aplasia associated with cotrimoxazole].
Med Clin (Barc). 1985 Mar 2;84(8):334.
6
Editorial: Co-trimoxazole and blood.
Lancet. 1973 Oct 27;2(7835):950-1.
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Letter: Co-trimoxazole and the blood.
Lancet. 1974 Aug 3;2(7875):284-5. doi: 10.1016/s0140-6736(74)91440-8.
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Letter: Long-term co-trimoxazole and folate depletion.
J Antimicrob Chemother. 1975 Sep;1(3):346. doi: 10.1093/jac/1.3.346.
9
Benefits and risks of co-trimoxazole (Bactrim) therapy.复方新诺明（百炎净）治疗的益处与风险。
Infection. 1987;15 Suppl 5:S221-66.
10
A multi-centre study comparing trimethoprim with co-trimoxazole in the treatment of respiratory tract infection in general practice.一项在全科医疗中比较甲氧苄啶与复方新诺明治疗呼吸道感染的多中心研究。
Br J Clin Pract. 1982 Apr;36(4):152-6.

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Pure red cell hypoplasia secondary to isoniazid.异烟肼继发的纯红细胞再生障碍。
Postgrad Med J. 1987 Apr;63(738):309-10. doi: 10.1136/pgmj.63.738.309.
2
Co-trimoxazole red cell aplasia in leukaemia.白血病中的复方新诺明所致纯红细胞再生障碍
Arch Dis Child. 1987 Jan;62(1):85-7. doi: 10.1136/adc.62.1.85-a.

本文引用的文献

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5-BENZYL-2,4-DIAMINOPYRIMIDINES AS ANTIBACTERIAL AGENTS. I. SYNTHESIS AND ANTIBACTERIAL ACTIVITY IN VITRO.5-苄基-2,4-二氨基嘧啶类抗菌剂。I. 体外合成与抗菌活性
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Neutropenia after trimethoprism-sulphamethoxazole for bronchitis.服用甲氧苄啶-磺胺甲恶唑治疗支气管炎后出现中性粒细胞减少症。
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Agranulocytosis after trimethoprim and sulphamethoxazole.甲氧苄啶和磺胺甲恶唑导致的粒细胞缺乏症。
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Trimethoprim: laboratory and clinical studies.甲氧苄啶：实验室研究与临床研究
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Haematological changes in a patient on long-term treatment with a trimethoprim-sulphonamide combination.一名长期接受甲氧苄啶 - 磺胺类药物联合治疗患者的血液学变化
Postgrad Med J. 1970 Dec;46(542):723-6. doi: 10.1136/pgmj.46.542.723.
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Thrombocytopenia following administration of "septrin".
Med J Aust. 1970 Oct 17;2(16):754. doi: 10.5694/j.1326-5377.1970.tb63154.x.
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Thrombocytopenia following administration of 'Bactrim'.
Med J Aust. 1970 Jul 25;2(4):200.
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Effects of trimethoprim on folate metabolism in man.
Clin Pharmacol Ther. 1968 Sep-Oct;9(5):550-60. doi: 10.1002/cpt196895550.
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Trimethoprim, a sulphonamide potentiator.甲氧苄啶，一种磺胺增效剂。
Br J Pharmacol Chemother. 1968 May;33(1):72-90. doi: 10.1111/j.1476-5381.1968.tb00475.x.