Leigh J M, Maynard J P
Br Med J. 1979 May 5;1(6172):1173-4. doi: 10.1136/bmj.1.6172.1173.
During cuffed intubation, damage to the trachea is least likely when the lateral wall pressure exerted by the cuff does not exceed the mean capillary perfusion pressure of the mucosa. A study was carried out of eight different types of endotracheal tubes. At the seal point the traditional red rubber tube and the armoured latex and Softway tubes exerted pressures above the mean systemic arterial pressure. Although the Portex and Mallinckrodt tubes exerted pressures close to the mean capillary perfusion pressure, much higher pressures resulted if they were overinflated. The Lanz tube, however, with its over-pressure safety balloon, maintained a lateral wall pressure below the mean capillary perfusion pressure even when inflated considerably beyond the seal point. Endotracheal cuffs are often overinflated in clinical practice. Since cuff-induced tracheal damage is most influenced by the lateral wall pressure, these results suggest that the use of Lanz-type tubes should be mandatory in intensive care units or when a cuffed tracheostomy tube is required and they should also be considered for use in more routine anaesthetic practice.
在使用带套囊气管插管时,当套囊施加的侧壁压力不超过黏膜平均毛细血管灌注压时,气管受损的可能性最小。对八种不同类型的气管内导管进行了一项研究。在密封点时,传统的红色橡胶导管、铠装乳胶导管和Softway导管施加的压力高于平均体动脉压。尽管Portex导管和Mallinckrodt导管施加的压力接近平均毛细血管灌注压,但如果过度充气,压力会高得多。然而,带有超压安全气囊的Lanz导管,即使充气量大大超过密封点,其侧壁压力仍保持在平均毛细血管灌注压以下。在临床实践中,气管内套囊常常过度充气。由于套囊引起的气管损伤受侧壁压力影响最大,这些结果表明,在重症监护病房或需要使用带套囊的气管造口管时,应强制使用Lanz型导管,在更常规的麻醉实践中也应考虑使用。