某健康区的医院抗生素政策
Hospital antibiotic policy in a health district.
作者信息
Lacey R W
出版信息
Br Med J. 1979 May 26;1(6175):1389-91. doi: 10.1136/bmj.1.6175.1389.
A hospital antibiotic policy is described in which only a few antibiotics were used over a two-year period. Six antibiotics--namely, ampicillin, cloxacillin, cephradine, penicillin, erythromycin, and oxytetracycline--accounted for 98% of the antibiotics consumed. Gentamicin was not used topically. Apart from high levels of resistance to ampicillin in Staphylococcus aureus (80%), the Enterobacteriaceae (37%), and Bacteroides (83%), antibiotic resistance was not a problem and no major epidemics of cross-infection occurred. With this policy antibiotic consumption declined and the total true cost of the antibiotics fell from 16 361 pounds in 1976 to 10 448 pounds in 1978.
本文描述了一项医院抗生素政策，即在两年期间仅使用了少数几种抗生素。六种抗生素——即氨苄西林、氯唑西林、头孢拉定、青霉素、红霉素和土霉素——占所消耗抗生素的98%。庆大霉素未用于局部治疗。除了金黄色葡萄球菌（80%）、肠杆菌科细菌（37%）和拟杆菌（83%）对氨苄西林的高耐药性外，抗生素耐药性不是一个问题，也没有发生重大的交叉感染流行。通过这项政策，抗生素消耗量下降，抗生素的总实际成本从1976年的16361英镑降至1978年的10448英镑。
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