氯贝丁酯处理的大鼠从血液中清除乙醇的速率增加。
The increased rate of ethanol removal from blood of clofibrate-treated rats.
作者信息
Hawkins R A, Nielsen R C, Veech R L
出版信息
Biochem J. 1974 Apr;140(1):117-20. doi: 10.1042/bj1400117.
Abstract
After ethanol injection similar metabolite changes were found in livers of clofibrate-treated and non-treated rats. The rate of ethanol removal from blood of clofibrate-treated rats was increased by 50%, but this was directly proportional to the increased liver size caused by clofibrate. No other difference needs to be postulated to explain the increased rate of ethanol removal from blood.
摘要
乙醇注射后，在氯贝丁酯治疗组和未治疗组大鼠的肝脏中发现了类似的代谢物变化。氯贝丁酯治疗组大鼠血液中乙醇的清除率提高了50%，但这与氯贝丁酯导致的肝脏增大直接相关。无需假定其他差异来解释血液中乙醇清除率的提高。
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Determination of citrate with citrate lyase.用柠檬酸裂解酶测定柠檬酸。
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Ethanol metabolism in rats treated with ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate).用乙基-α-对氯苯氧异丁酸酯（氯贝丁酯）处理的大鼠的乙醇代谢
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