狗胃中N-亚硝基吡咯烷的形成。
Formation of N-nitrosopyrrolidine in a dog's stomach.
作者信息
Mysliwy T S, Wick E L, Archer M C, Shank R C, Newberne P M
出版信息
Br J Cancer. 1974 Sep;30(3):279-83. doi: 10.1038/bjc.1974.192.
Abstract
The formation of N-nitrosopyrrolidine from sodium nitrite and pyrrolidine in vivo in a dog's stomach is demonstrated. The rate of formation of nitrosopyrrolidine is shown to be subject to pronounced catalytic effects. Nitrosopyrrolidine is also shown to disappear rapidly from the stomach, probably due to absorption.
摘要
已证实在狗的胃内亚硝酸钠和吡咯烷在体内可形成N-亚硝基吡咯烷。结果表明，亚硝基吡咯烷的形成速率受到显著的催化作用影响。还表明亚硝基吡咯烷会迅速从胃中消失，这可能是由于吸收所致。
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