Andriole V T, Bonadio M, Bianchi C
Yale J Biol Med. 1974 Dec;47(4):268-76.
The influence of postural changes on renal function was determined in 13 patients with nephroptosis and in 5 normal subjects by measuring GFR in the erect and supine positions. The results indicate that GFR was reduced in the erect position in 10 of 13 patients with either unilateral or bilateral nephroptosis whereas GFR was increased in the erect position in 4 of 5 patients without renal disease. One patient with bilateral nephroptosis and renovascular hypertension was studied before and after surgical correction of his disease. These observations indicate that patients with nephroptosis may have significant reductions in renal function when they assume an upright position, and suggest that GFR measurements in the supine and erect position in patients with nephroptosis can be helpful in evaluating this disease.
通过测量13例肾下垂患者和5例正常受试者直立位和平卧位的肾小球滤过率（GFR），确定体位变化对肾功能的影响。结果表明，13例单侧或双侧肾下垂患者中有10例在直立位时GFR降低，而5例无肾脏疾病的患者中有4例在直立位时GFR升高。对1例双侧肾下垂合并肾血管性高血压的患者在手术矫正疾病前后进行了研究。这些观察结果表明，肾下垂患者在直立位时肾功能可能会显著降低，并提示对肾下垂患者进行平卧位和直立位GFR测量有助于评估该疾病。
