Searle A G, Beechey C V, Eicher E M, Nesbitt M N, Washburn L L
Cytogenet Cell Genet. 1979;23(4):255-63. doi: 10.1159/000131336.
The cytologic positions (determined by G-banding) of the breakpoints on mouse chromosome 2 of a series of ten reciprocal translocations were compared with their most probable genetic positions on the linkage map, as determined by studies on recombination with known chromosome 2 (= linkage group V) markers. The most probable proximaldistal orders of the genetic and cytologic breakpoints were found to be the same; i.e., the two sets of breakpoints were colinear. However, there was no close correspondence between these two measures of the distance apart of adjacent breakpoints, since some translocation breaks which were well separated in G-band positions seemed close together in terms of the linkage map, and vice versa. This helps to confirm LYON'S conclusion that in certain mouse chromosomes, including No. 2, the distribution of chiasmata is nonrandom.
将一系列十个相互易位中，小鼠2号染色体上断点的细胞学位置（通过G带分析确定），与其在连锁图谱上最可能的遗传位置进行了比较，后者是通过与已知的2号染色体（=连锁群V）标记的重组研究确定的。遗传断点和细胞学断点最可能的近端-远端顺序被发现是相同的；也就是说，两组断点是共线的。然而，相邻断点之间这两种距离衡量方法之间并没有密切的对应关系，因为一些在G带位置上相距很远的易位断点，在连锁图谱上看起来却靠得很近，反之亦然。这有助于证实莱昂的结论，即在某些小鼠染色体中，包括2号染色体，交叉的分布是非随机的。
