Toghill P J, Benton K P, Smith P G
Postgrad Med J. 1974 Jan;50(579):9-15. doi: 10.1136/pgmj.50.579.9.
In a series of 301 patients with ulcerative colitis forty-eight developed the disease before the age of 20. In this group of forty-eight patients there were four cases of serious chronic liver disease as compared with a total of seven cases of chronic liver disease in the whole series. The hepatic lesions in the patients developing colitis in childhood were unrelated to the extent, duration or severity of the colitis but colitis in very early life appeared to predispose to liver disease subsequently.
在一组301例溃疡性结肠炎患者中,48例在20岁之前发病。在这48例患者中,有4例患有严重的慢性肝病,而在整个系列中慢性肝病总共7例。儿童期患结肠炎患者的肝脏病变与结肠炎的范围、持续时间或严重程度无关,但早年的结肠炎似乎易导致随后发生肝病。