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商品名或批准名。第二点。观点。临床药理学家。

Trade names or approved names. Point II. Points of view. The clinical pharmacologist.

作者信息

Turner P

出版信息

Postgrad Med J. 1974 Feb;50(580):93-5. doi: 10.1136/pgmj.50.580.93.

Abstract

Differences in formulation are of greater clinical importance in the case of sparingly soluble drugs, those with small therapeutic doses, in replacement therapy and in the control of serious clinical conditions with compounds having a low therapeutic index: this subject should receive specific attention in medical teaching and in clinical trials.

摘要

对于难溶性药物、治疗剂量小的药物、替代疗法中的药物以及用治疗指数低的化合物控制严重临床病症时,制剂差异具有更大的临床重要性:在医学教学和临床试验中应特别关注这一主题。

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Trade names or approved names. Part II. Points of view. Europe.
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本文引用的文献

2
Formulation and therapeutic efficacy of drugs used in clinical trials.
Lancet. 1969 Jul 12;2(7611):98-9. doi: 10.1016/s0140-6736(69)92406-4.
3
Rate of dissolution of digoxin tablets as a predictor of absorption.
Lancet. 1973 Jun 30;1(7818):1473-5. doi: 10.1016/s0140-6736(73)91811-4.

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