[Study of pharmacological activity of potassium glutamate in an experiment on young and old animals].

It was established that potassium glutaminate is a little toxic compound (LD50 amounts to 4500 mg/kg on administration to white mice by mouth) and shows a marked pharmacological activity. Administration of potassium glutaminate to white rats in a dose 500 mg/kg raises intracellular potassium level in the tissues, makes the acid-balance equilibrium return to normal after unilateral nephrectomy and acid load, activates bile-forming and choleretic liver function, exerts a moderate diuretic effect. The compound potentiates the activity of succinate dehydrogenase and cytochromoxidase in the tissues of old rats.