合成蛋白-糖结合物作为特应性变应原补体灭活特性的模型。
Synthetic protein-sugar conjugates as models for the complement-inactivating property of atopic allergens.
作者信息
Berrens L, van Liempt P M
出版信息
Clin Exp Immunol. 1974 Aug;17(4):703-7.
Abstract
Synthetic conjugates of β-lactoglobulin and reducing sugar prepared by Maillard reaction acquire the capacity of inactivating haemolytic complement in human serum. The C-inactivating potential is related to the mean number of (lysine)-ε-amino-1-deoxy-2-ketose residues incorporated in the model compound. These findings are compared to results obtained by skin-testing similar artificial allergens in atopic subjects.
摘要
通过美拉德反应制备的β-乳球蛋白与还原糖的合成结合物具有使人血清中的溶血补体失活的能力。补体失活潜力与模型化合物中掺入的（赖氨酸）-ε-氨基-1-脱氧-2-酮糖残基的平均数有关。将这些发现与在特应性受试者中对类似人工过敏原进行皮肤测试所获得的结果进行了比较。
相似文献
1
Synthetic protein-sugar conjugates as models for the complement-inactivating property of atopic allergens.合成蛋白-糖结合物作为特应性变应原补体灭活特性的模型。
Clin Exp Immunol. 1974 Aug;17(4):703-7.
2
[Atopic allergens: atypical antigens?].
Ned Tijdschr Geneeskd. 1970 Aug 29;114(35):1446-52.
3
Food allergies.食物过敏。
R Soc Health J. 1970 Sep-Oct;90(5):243-7.
4
Inhibition of leucine and lysine aminopeptidase by atopic allergens.
Nature. 1968 Feb 17;217(5129):664-5. doi: 10.1038/217664a0.
5
Reduced T cell response to beta-lactoglobulin by conjugation with acidic oligosaccharides.通过与酸性寡糖结合降低T细胞对β-乳球蛋白的反应。
J Agric Food Chem. 2005 Aug 24;53(17):6851-7. doi: 10.1021/jf050772k.
6
Studies on hyperimmunoglobulinaemia E in atopic diseases with particular reference to food allergens.关于特应性疾病中高免疫球蛋白E血症的研究，特别涉及食物过敏原。
Clin Exp Immunol. 1981 Oct;46(1):54-60.
7
Cross-sensitization between synthetic primin and related quinones.
Acta Derm Venereol. 1969;49(6):552-5.
8
Differential protein expression by dendritic cells from atopic and non-atopic individuals after stimulation by the major house dust mite allergen Der p 1.主要屋尘螨变应原Der p 1刺激后，特应性和非特应性个体的树突状细胞的差异蛋白表达
Int Arch Allergy Immunol. 2009;150(3):237-51. doi: 10.1159/000222676. Epub 2009 Jun 4.
9
[Results of skin prick tests and evaluation of serum antigen specific immunoglobulin E in patients with atopic dermatitis and airborne allergy with regards to the type of sensitising allergens and seasonal course of the disease].[特应性皮炎和空气传播性过敏患者皮肤点刺试验结果及血清抗原特异性免疫球蛋白E评估：致敏变应原类型及疾病的季节性病程]
Pol Merkur Lekarski. 2005 Apr;18(106):393-9.
10
Latex sensitivity among hospital employees and atopic children.医院员工和特应性儿童中的乳胶敏感性。
Turk J Pediatr. 1998 Jan-Mar;40(1):61-8.
本文引用的文献
1
Improved method for the preparation of crystalline beta-lactoglobulin and alpha-lactalbumin from cow's milk.从牛奶中制备结晶β-乳球蛋白和α-乳白蛋白的改进方法。
Biochem J. 1957 Feb;65(2):273-7. doi: 10.1042/bj0650273.
2
Synthetic approaches to the biological activity of beta-lactoglobulin in human allergy to cows' milk.
Nature. 1966 Oct 29;212(5061):541-3. doi: 10.1038/212541a0.
3
Identification of the atopic allergen in cow's milk.
Int Arch Allergy Appl Immunol. 1968;34(6):521-43. doi: 10.1159/000230147.
4
Inactivation of complement (C3) in human serum by atopic allergens.特应性变应原对人血清中补体（C3）的灭活作用。
Int Arch Allergy Appl Immunol. 1973;45(1):30-9. doi: 10.1159/000230996.
5
An analytical approach to the frequency distribution of positive skin reactions to atopic allergens.
Ann Allergy. 1971 Mar;29(3):118-25.
6
The chemical classification of atopic allergens: an attempt at integration.
Int Arch Allergy Appl Immunol. 1971;41(1):186-98. doi: 10.1159/000230517.
Zotero 插件