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在白细胞迁移试验中，颗粒性卡介苗相对于可溶性结核菌素纯蛋白衍生物抗原的优越性。

Superiority of corpuscular BCG to soluble PPD antigen in the leucocyte migration assay.

作者信息

Górski A J

出版信息

Clin Exp Immunol. 1974 Sep;18(1):149-53.

PMID:4469226
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1537965/
Abstract

The recognized trend towards the standardization of the leucocyte migration assay prompted the comparison of efficacy of BCG with soluble purified protein derivative (PPD) antigens in this test. Even low BCG concentrations permit high correlations between and responses, whilst PPD doses needed to elicit comparable reactions fall within toxic concentrations. BCG-induced inhibition of leucocyte migration is abolished by the protein synthesis inhibitor, cycloheximide.

摘要

白细胞迁移试验标准化的公认趋势促使在该试验中比较卡介苗与可溶性纯化蛋白衍生物（PPD）抗原的功效。即使是低浓度的卡介苗也能使[具体内容缺失]和[具体内容缺失]反应之间具有高度相关性，而引发类似反应所需的PPD剂量却处于有毒浓度范围内。卡介苗诱导的白细胞迁移抑制作用可被蛋白质合成抑制剂环己酰亚胺消除。

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Superiority of corpuscular BCG to soluble PPD antigen in the leucocyte migration assay.在白细胞迁移试验中，颗粒性卡介苗相对于可溶性结核菌素纯蛋白衍生物抗原的优越性。
Clin Exp Immunol. 1974 Sep;18(1):149-53.
2
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Eur J Immunol. 1976 Mar;6(3):163-7. doi: 10.1002/eji.1830060305.

引用本文的文献

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Clin Exp Immunol. 1986 Dec;66(3):516-24.
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A study of the aetiology of gastritis following gastric surgery. II. Studies of cell-mediated immunity.胃手术后胃炎病因学研究。II. 细胞介导免疫研究。
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本文引用的文献

1
Migration inhibitory factor and interferon in the circulation of mice with delayed hypersensitivity.循环中迁移抑制因子和干扰素与小鼠迟发型超敏反应。
Infect Immun. 1973 Jan;7(1):68-75. doi: 10.1128/iai.7.1.68-75.1973.
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Evaluation of the leucocyte migration test as a measure of delayed hypersensitivty in man. Suppression of migration inhibition by puromycin.作为人类迟发型超敏反应指标的白细胞迁移试验的评估。嘌呤霉素对迁移抑制的抑制作用。
Clin Exp Immunol. 1972 Aug;11(4):535-41.
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Cell Immunol. 1973 Jul;8(1):162-5. doi: 10.1016/0008-8749(73)90103-2.
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Standardization of the leucocyte migration test.白细胞迁移试验的标准化
Int Arch Allergy Appl Immunol. 1973;45(1):308-21. doi: 10.1159/000231048.
7
Mechanism of buffy coat migration inhibition test.血沉棕黄层游走抑制试验的机制。
Experientia. 1973 Mar 15;29(3):340-1. doi: 10.1007/BF01926517.
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Reactivity of human lymphocytes to aggregated and nonaggregated PPD-tuberculin.
Cell Immunol. 1972 Dec;5(4):555-60. doi: 10.1016/0008-8749(72)90105-0.
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The fate of corpuscular antigen in leukocyte migration cultures.白细胞迁移培养中颗粒性抗原的命运
Transplant Proc. 1972 Jun;4(2):253-8.
10
In vitro methods in cell-mediated immunity: a progress report.细胞介导免疫的体外方法：进展报告。
Cell Immunol. 1973 Mar;6(3):331-47. doi: 10.1016/0008-8749(73)90034-8.