葡萄糖刺激的胰岛素释放的异头物特异性：存在葡萄糖受体的证据？
Anomeric specificity of glucose-stimulated insulin release: evidence for a glucoreceptor?
作者信息
Grodsky G M, Fanska R, West L, Manning M
出版信息
Science. 1974 Nov 8;186(4163):536-8. doi: 10.1126/science.186.4163.536.
PMID:4469677
Abstract
The effects on insulin secretion of alpha and beta anomers of D-glucose were studied in the in vitro perfused rat pancreas. Both phases of insulin release showed consistent stereospecificity for alpha-glucose; this specificity indicates an action of glucose independent of intracellular glucose metabolism.
摘要
在体外灌注大鼠胰腺中研究了D-葡萄糖的α和β异头物对胰岛素分泌的影响。胰岛素释放的两个阶段对α-葡萄糖均表现出一致的立体特异性；这种特异性表明葡萄糖的作用独立于细胞内葡萄糖代谢。
Zotero 插件