Pulsatile growth hormone secretion: suppression by hypothalamic ventromedial lesions and by long-acting somatostatin.
作者信息
Martin J B, Renaud L P, Brazeau P
出版信息
Science. 1974 Nov 8;186(4163):538-40. doi: 10.1126/science.186.4163.538.
PMID:4469678
Abstract
Sequential blood samples, obtained from freely behaving, nonstressed male rats, showed a pulsatile pattern of growth hormone secretion with a mean interval between peaks of 68 minutes. The bursts of secretion were blocked by lesions of the hypothalamic ventromedial nuclei and by administration of a longacting preparation of synthetic somatostatin.
摘要
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