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外周血淋巴细胞培养在药物性肝损伤诊断中的应用

Peripheral lymphocyte culture in the diagnosis of drug induced liver injury.

作者信息

Kato Y, Kobayashi K, Hattori N, Takeuchi J, Ota G

出版信息

Gastroenterol Jpn. 1979;14(3):216-25. doi: 10.1007/BF02774070.

DOI:10.1007/BF02774070
PMID:447001
Abstract

In order to evaluate the usefulness of the peripheral lymphocyte culture method for the diagnosis of drug-induced liver injury, a study was carried out on 21 cases of drug-induced liver injury (Group A). Nine cases in Group A showed a positive lymphocyte stimulation test. Out of 9 cases which showed positive stimulation six cases were cholestatic type of liver injury, and the remaining three were of hepatitic type. The results suggest that peripheral lymphocyte culture method is a useful method for diagnosis of drug-induced liver injury.

摘要

为了评估外周淋巴细胞培养方法在药物性肝损伤诊断中的实用性,对21例药物性肝损伤患者(A组)进行了一项研究。A组中有9例淋巴细胞刺激试验呈阳性。在9例刺激试验呈阳性的病例中,6例为胆汁淤积型肝损伤,其余3例为肝炎型。结果表明,外周淋巴细胞培养方法是诊断药物性肝损伤的一种有用方法。

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Peripheral lymphocyte culture in the diagnosis of drug induced liver injury.外周血淋巴细胞培养在药物性肝损伤诊断中的应用
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