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通过二维免疫电泳对五种利用精氨酸的支原体进行血清学比较。

Serological comparison of five arginine-utilizing Mycoplasma species by two-dimensional immunoelectrophoresis.

作者信息

Thirkill C E, Kenny G E

出版信息

Infect Immun. 1974 Sep;10(3):624-32. doi: 10.1128/iai.10.3.624-632.1974.

DOI:10.1128/iai.10.3.624-632.1974
PMID:4473427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC422997/
Abstract

Five arginine-utilizing, nonglycolytic Mycoplasma species were compared serologically by two dimensional immunoelectrophoresis. The survey included: Mycoplasma hominis, Mycoplasma arthritidis, Mycoplasma gateae, Mycoplasma gallinarum, and three strains of Mycoplasma arginini. Although the M. arginini strains showed strong cross-reactions, each strain produced a different antigenic profile which was distinct and which indicated significant antigenic differences between strains. The M. arginini strains showed strong relationships with M. gateae; lesser cross-reactions were observed with other strains. Common antigens were demonstrable in the entire group. When all these species were compared with a glycolytic species, Mycoplasma gallisepticum, no cross-reactions were observed. Two-dimensional immunoelectrophoresis was a far more sensitive technique than double-immunodiffusion since as many as 20 components could be resolved.

摘要

通过二维免疫电泳对5种利用精氨酸、非糖酵解的支原体进行了血清学比较。调查包括:人型支原体、关节炎支原体、加泰罗尼亚支原体、鸡支原体以及3株精氨酸支原体。虽然精氨酸支原体菌株显示出强烈的交叉反应,但每个菌株产生不同的抗原图谱,该图谱是独特的,表明菌株之间存在显著的抗原差异。精氨酸支原体菌株与加泰罗尼亚支原体显示出很强的相关性;与其他菌株观察到较弱的交叉反应。在整个组中都能证明存在共同抗原。当将所有这些物种与糖酵解物种鸡败血支原体进行比较时,未观察到交叉反应。二维免疫电泳是一种比双向免疫扩散灵敏得多的技术,因为可以分辨多达20种成分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/7dc4d387f498/iai00249-0220-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/a6082966b63d/iai00249-0215-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/3053a2dbc4b3/iai00249-0216-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/506891f18d77/iai00249-0218-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/7dc4d387f498/iai00249-0220-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/a6082966b63d/iai00249-0215-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/3053a2dbc4b3/iai00249-0216-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/506891f18d77/iai00249-0218-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d25b/422997/7dc4d387f498/iai00249-0220-a.jpg

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