苯并(a)芘的代谢活化通过二醇环氧化物进行。 - Suppr

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超能文献

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide.

作者信息

Sims P, Grover P L, Swaisland A, Pal K, Hewer A

出版信息

Nature. 1974 Nov 22;252(5481):326-8. doi: 10.1038/252326a0.

DOI:10.1038/252326a0

PMID:4473724

Abstract

摘要

相似文献

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide.苯并(a)芘的代谢活化通过二醇环氧化物进行。

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Metabolic activation of benzo(a)pyrene and binding to DNA in cultured human bronchus.苯并(a)芘在培养的人支气管中的代谢活化及与DNA的结合。

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Metabolism and macromolecular binding of carcinogenic and noncarcinogenic metabolites of benzo(a)pyrene by hamster embryo cells.仓鼠胚胎细胞对苯并(a)芘致癌和非致癌代谢产物的代谢及大分子结合

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Quantitative significance of glutathione and glutathione-S-transferase in regulating benzo[a]pyrene anti diol-epoxide level in reconstituted C3H/10T1/2 cell lysates, and comparison to rat liver.谷胱甘肽和谷胱甘肽-S-转移酶在调节重组C3H/10T1/2细胞裂解物中苯并[a]芘反式二醇环氧化物水平方面的定量意义，以及与大鼠肝脏的比较。

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Inhibitory effect of 3-hydroxybenzo(a)pyrene on the mutagenicity and tumorigenicity of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene.3-羟基苯并(a)芘对(±)-7β,8α-二羟基-9α,10α-环氧-7,8,9,10-四氢苯并(a)芘的致突变性和致癌性的抑制作用

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Comparison of the cellular DNA-bound products of benzo(alpha)pyrene with the products formed by the reaction of benzo(alpha)pyrene-4,5-oxide with DNA.

Cancer Res. 1975 Jan;35(1):54-7.

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