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The underlying insulin receptor in patients with antireceptor autoantibodies: demonstration of normal binding and immunological properties.

作者信息

Muggeo M, Kahn C R, Bar R S, Rechler M, Flier J S, Roth J

出版信息

J Clin Endocrinol Metab. 1979 Jul;49(1):110-9. doi: 10.1210/jcem-49-1-110.

DOI:10.1210/jcem-49-1-110
PMID:447809
Abstract
摘要

相似文献

1
The underlying insulin receptor in patients with antireceptor autoantibodies: demonstration of normal binding and immunological properties.抗受体自身抗体患者体内的潜在胰岛素受体：正常结合和免疫特性的证明。
J Clin Endocrinol Metab. 1979 Jul;49(1):110-9. doi: 10.1210/jcem-49-1-110.
2
The evolving clinical course of patients with insulin receptor autoantibodies: spontaneous remission or receptor proliferation with hypoglycemia.胰岛素受体自身抗体患者不断演变的临床病程：自发缓解或受体增殖伴低血糖。
J Clin Endocrinol Metab. 1978 Nov;47(5):985-95. doi: 10.1210/jcem-47-5-985.
3
Receptors, antireceptor antibodies and mechanisms of insulin resistance.受体、抗受体抗体与胰岛素抵抗机制
N Engl J Med. 1979 Feb 22;300(8):413-9. doi: 10.1056/NEJM197902223000808.
4
Atypical antiinsulin receptor antibodies in a patient with type B insulin resistance and scleroderma.一名患有B型胰岛素抵抗和硬皮病患者体内的非典型抗胰岛素受体抗体。
J Clin Endocrinol Metab. 1989 Jan;68(1):227-31. doi: 10.1210/jcem-68-1-227.
5
[Antireceptor antibodies and insulin resistance. The B type syndrome].[抗受体抗体与胰岛素抵抗。B型综合征]
Recenti Prog Med. 1980 Feb;68(2):189-99.
6
Insulin modulation of antibody-dependent cytotoxicity and the detection of antireceptor antibodies.胰岛素对抗体依赖性细胞毒性的调节作用及抗受体抗体的检测
J Lab Clin Med. 1982 Jan;99(1):39-45.
7
Direct method for detection and characterization of cell surface receptors for insulin by means of 125I-labeled autoantibodies against the insulin receptor.利用抗胰岛素受体的125I标记自身抗体检测和鉴定胰岛素细胞表面受体的直接方法。
Proc Natl Acad Sci U S A. 1976 Nov;73(11):4115-9. doi: 10.1073/pnas.73.11.4115.
8
Autoantibodies to the insulin receptor. Effect on the insulin-receptor interaction in IM-9 lymphocytes.胰岛素受体自身抗体。对IM-9淋巴细胞中胰岛素-受体相互作用的影响。
J Clin Invest. 1977 Oct;60(4):784-94. doi: 10.1172/JCI108832.
9
Syndromes of autoimmunity and hypoglycemia. Autoantibodies directed against insulin and its receptor.自身免疫与低血糖综合征。针对胰岛素及其受体的自身抗体。
Endocrinol Metab Clin North Am. 1989 Mar;18(1):123-43.
10
Anti-receptor antibodies mimic the effect of insulin to down-regulate insulin receptors in cultured human lymphoblastoid (IM-9) cells.抗受体抗体可模拟胰岛素的作用，下调培养的人淋巴母细胞样（IM-9）细胞中的胰岛素受体。
J Clin Endocrinol Metab. 1984 Jan;58(1):182-6. doi: 10.1210/jcem-58-1-182.

引用本文的文献

1
Stimulation of glucose incorporation and amino acid transport by insulin and an insulin-like growth factor in fibroblasts with defective insulin receptors cultured from a patient with leprechaunism.来自一名妖精貌综合征患者的胰岛素受体缺陷型成纤维细胞中，胰岛素和一种胰岛素样生长因子对葡萄糖掺入及氨基酸转运的刺激作用。
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2554-8. doi: 10.1073/pnas.78.4.2554.
2
Antibody-induced desensitization of the insulin receptor. Studies of the mechanism of desensitization in 3T3-L1 fatty fibroblasts.抗体诱导的胰岛素受体脱敏。3T3-L1脂肪成纤维细胞中脱敏机制的研究。
J Clin Invest. 1980 Nov;66(5):1124-34. doi: 10.1172/JCI109942.
3
Characterization of insulin receptors in patients with the syndromes of insulin resistance and acanthosis nigricans.
胰岛素抵抗和黑棘皮症综合征患者胰岛素受体的特征分析
Diabetologia. 1980 Mar;18(3):209-16. doi: 10.1007/BF00251918.
4
Insulin receptor degradation is accelerated in cultured lymphocytes from patients with genetic syndromes of extreme insulin resistance.在患有极端胰岛素抵抗遗传综合征患者的培养淋巴细胞中，胰岛素受体降解加速。
J Clin Invest. 1984 Oct;74(4):1366-74. doi: 10.1172/JCI111547.
5
Antibody against the insulin receptor causes disappearance of insulin receptors in 3T3-L1 cells: a possible explanation of antibody-induced insulin resistance.抗胰岛素受体抗体导致3T3-L1细胞中胰岛素受体消失：抗体诱导胰岛素抵抗的一种可能解释。
Proc Natl Acad Sci U S A. 1984 Apr;81(8):2508-11. doi: 10.1073/pnas.81.8.2508.
6
Pathogenetic mechanisms of hereditary diabetes mellitus.遗传性糖尿病的发病机制。
Hum Genet. 1983;63(2):100-6. doi: 10.1007/BF00291526.
7
Autoantibodies to hormone receptors.
Springer Semin Immunopathol. 1982;5(4):447-62. doi: 10.1007/BF01857430.
8
Antibodies directed to the insulin receptor. Clinical aspects and applications to the study of insulin action.针对胰岛素受体的抗体。临床方面及其在胰岛素作用研究中的应用。
J Endocrinol Invest. 1990 Dec;13(11):951-68. doi: 10.1007/BF03349669.
9
Primary defect of insulin receptors in skin fibroblasts cultured from an infant with leprechaunism and insulin resistance.从一名患脂肪代谢障碍和胰岛素抵抗的婴儿培养的皮肤成纤维细胞中胰岛素受体的原发性缺陷。
Proc Natl Acad Sci U S A. 1979 Nov;76(11):5877-81. doi: 10.1073/pnas.76.11.5877.