Strong M S, Vaughan C W, Healy G B, Shapshay S M, Jako G J
Laryngoscope. 1979 Jun;89(6 Pt 1):897-905. doi: 10.1288/00005537-197906000-00005.
Since 1972 we have been cautiously exploring the use of CO2 laser in the management of carefully selected cases of localized carcinoma of the oral cavity. At the present time our experience is based on the treatment of 57 patients with cancer of the oral cavity. The CO2 laser has been found to be an indispensable tool in the transoral management of T1 carcinomas, multiple superficial carcinoma, extensive leukoplakia and verrucous carcinoma. The laser allows precise excision of the lesion and involved mucosa and provides and excellent specimen for histologic verification of the margins. The morbidity of laser excision is minimal, so that a tracheotomy is not needed and patients can almost always be discharged on the following day. (Follow-up data on those patients at risk for 30 months indicate excellent control rates).
自1972年以来，我们一直在谨慎地探索二氧化碳激光在精心挑选的口腔局部癌病例治疗中的应用。目前，我们的经验基于对57例口腔癌患者的治疗。二氧化碳激光已被证明是经口治疗T1期癌、多发性浅表癌、广泛性白斑和疣状癌不可或缺的工具。激光能够精确切除病变及受累黏膜，并提供用于切缘组织学验证的优质标本。激光切除的发病率极低，因此无需气管切开术，患者几乎总能在次日出院。（对这些有风险患者30个月的随访数据显示控制率极佳）
