Butcher R B
Laryngoscope. 1979 Jul;89(7 Pt 1):1092-8.
Keratoacanthoma is generally considered to be a benign cutaneous lesion with initial rapid growth and spontaneous involution over several months. It is not generally appreciated that the keratoacanthoma may have a malignant potential or be associated with carcinoma. When a lesion diagnosed as keratoacanthoma recurs after excision, underlying malignancy must be considered. Four examples of keratoacanthoma associated with underlying malignancy are presented from the Ochsner Medical Institutions to emphasize the above points.
角化棘皮瘤通常被认为是一种良性皮肤病变，起初生长迅速，数月内可自行消退。人们一般并不了解角化棘皮瘤可能具有恶性潜能或与癌症相关。当诊断为角化棘皮瘤的病变在切除后复发时，必须考虑潜在的恶性肿瘤。奥克斯纳医疗机构提供了4例与潜在恶性肿瘤相关的角化棘皮瘤病例，以强调上述要点。
