Levy D W, Bonakdarpour A, Putong P B, Mesgarzadeh M, Betz R R
Skeletal Radiol. 1985;13(4):287-90. doi: 10.1007/BF00355351.
The subungual keratoacanthoma is a benign neoplasm which simulates and must be differentiated from squamous cell carcinoma. Subungual keratoacanthomas are rapidly growing tumors, causing bone destruction which usually heal spontaneously. The lesion most often presents as a painful, enlarging mass in middle-aged Caucasian patients. Radiographic examination demonstrates a lytic cup-shaped erosion of the underlying distal phalanx. It is essential to recognize keratoacanthoma and separate it from squamous cell carcinoma, both for prognostic and therapeutic reasons. We present two cases of proven subungual keratoacanthoma and discuss their radiographic and histologic characteristics, as well as the current treatment alternatives for this entity.
甲下角化棘皮瘤是一种良性肿瘤，它具有类似鳞状细胞癌的表现，必须与之鉴别。甲下角化棘皮瘤是快速生长的肿瘤，可导致骨质破坏，通常能自发愈合。该病变最常表现为中年白种人患者中一个疼痛性、不断增大的肿块。影像学检查显示其下方远节指骨有溶骨性杯状侵蚀。出于预后和治疗的原因，识别角化棘皮瘤并将其与鳞状细胞癌区分开来至关重要。我们报告两例经证实的甲下角化棘皮瘤病例，并讨论其影像学和组织学特征，以及针对该疾病目前的治疗选择。
