Sroczyński J, Wegiel A, Pigoń-Wegiel A
Med Pr. 1979;30(1):41-7.
The authors examined the blood coagulation system in the following 3 groups of workers occupationally exposed to noise and vibration: A--those in whom the examination was conducted 7--16 hrs after finishing the work, B--those in whom the examination was conducted at the 3rd or 4th hour of work, and C--those suffering from angioneurosis of the vibration syndrome of II or III period who have not been exposed to vibration for some recent years. These investigations indicated the lack of blood equilibrium tending to hypercoagulability, shortened duration of plasma recalcination, increased elasticity coefficient of mE thromboelastogram coagulation, increased fibrinogen concentration; these changes were most evident in the group with advanced vibration disease and in those in whom the examination was conducted at their working time. Fibrinolysis duration was significantly prolonged during work, and shortened in those with advanced angioneurosis. In the opinion of the authors, those disturbances in the blood equilibrium system may be accounted for by the conformation changes of proteins.
作者对以下3组职业性接触噪声和振动的工人的凝血系统进行了检查：A组——在工作结束后7至16小时进行检查的工人；B组——在工作第3或第4小时进行检查的工人；C组——患有II期或III期振动综合征血管神经症且近年来未接触过振动的工人。这些研究表明，存在血液平衡倾向于高凝状态、血浆复钙时间缩短、mE血栓弹力图凝血弹性系数增加、纤维蛋白原浓度增加的情况；这些变化在患有晚期振动病的组以及在工作时间进行检查的组中最为明显。工作期间纤维蛋白溶解时间显著延长，而在患有晚期血管神经症的工人中则缩短。作者认为，血液平衡系统的这些紊乱可能是由蛋白质构象变化引起的。
