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职业性铅中毒受试者的生化与电生理研究

[Biochemical and electrophysiological studies in subjects with occupational exposure to lead poisoning].

作者信息

Kazibutowska Z, Mierzwa P, Mierzwa E

出版信息

Neurol Neurochir Pol. 1979 Mar-Apr;13(2):155-62.

PMID:450179
Abstract

In 36 men working in occupations with lead exposure the conduction velocity was measured in the motor fibres of the median, ulnar and peroneal nerves, and determinations were carried out of blood lead level, 24-hour urinary excretion of lead and delta-aminolaevulinic acid, and activity of delta-aminolaevulinic acid dehydratase in the erythrocytes. The comparison of the results of electrophysiological and biochemical investigations shows that lesions of the peripheral nervous system are not always correlated with the biochemical indices of lead poisoning and that peripheral nervous system damage, mainly subclinical, may develop in early period of exposure.

摘要

对36名从事铅暴露职业的男性,测量了正中神经、尺神经和腓总神经运动纤维的传导速度,并测定了血铅水平、24小时尿铅和δ-氨基乙酰丙酸排泄量以及红细胞中δ-氨基乙酰丙酸脱水酶的活性。电生理和生化研究结果的比较表明,周围神经系统损伤并不总是与铅中毒的生化指标相关,并且在接触铅的早期可能会发生主要为亚临床的周围神经系统损害。

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