同卵双胞胎中白血病淋巴母细胞与正常淋巴细胞之间的“抗原性”差异。
'Antigenic' disparity between leukaemic lymphoblasts and normal lymphocytes in identical twins.
作者信息
Han T, Wang J
出版信息
Clin Exp Immunol. 1972 Oct;12(2):171-5.
Abstract
Circulating lymphocytes of a normal boy were unequivocally stimulated by irradiated leukaemic lymphoblasts from his identical twin with acute lymphoblastic leukaemia. This reaction indicates that there is an `antigenic' disparity between these two types of cells. It is possible that leukaemic cells may acquire new surface antigens or that existing surface antigens of lymphoid cells may be modified during the process of leukaemogenesis.
摘要
一名正常男孩的循环淋巴细胞受到来自其同卵双胞胎患急性淋巴细胞白血病的白血病淋巴母细胞的明确刺激。这种反应表明这两种细胞之间存在“抗原”差异。白血病细胞可能获得新的表面抗原，或者淋巴细胞现有的表面抗原在白血病发生过程中可能发生改变。
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'Antigenic' disparity between leukaemic lymphoblasts and normal lymphocytes in identical twins.同卵双胞胎中白血病淋巴母细胞与正常淋巴细胞之间的“抗原性”差异。
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引用本文的文献
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Leukaemia antigens: mixed leucocyte culture tests on twelve leukaemic patients with identical twins.白血病抗原：对12名白血病患者与其同卵双胞胎进行的混合淋巴细胞培养试验。
Clin Exp Immunol. 1974 Oct;18(2):237-42.
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Stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.肿瘤细胞在体外对同基因和异基因淋巴细胞的刺激作用。
Br J Cancer. 1975 Jul;32(1):5-15. doi: 10.1038/bjc.1975.127.
本文引用的文献
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A simple micro cytotoxicity test.一种简单的微量细胞毒性试验。
Transplantation. 1969 Mar;7(3):220-3. doi: 10.1097/00007890-196903000-00023.
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Recognition of leukaemia cells as foreign before and after autoimmunization.自身免疫前后对白血病细胞作为外来物的识别。
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Demonstration of cell-mediated immunity to human neoplasms of various histological types.对各种组织学类型的人类肿瘤的细胞介导免疫的证明。
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Enhanced immune response to leukaemia.对白血病的免疫反应增强。
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