Wells D M, James O B
J Hyg (Lond). 1973 Mar;71(1):209-15. doi: 10.1017/s0022172400046374.
The antibiotic resistance patterns of coliforms in faecal specimens from pigs and their human contacts were studied. The ability of the resistant coliforms to transfer their resistance in vitro to antibiotic-sensitive recipients was examined. The results showed that pigs which had received antibiotics carried more multiply-resistant, R-factor bearing coliforms than pigs which had not been given antibiotics. Human contacts of the antibiotic-treated pigs had a higher incidence of antibiotic-resistant coliforms with R-factors than human contacts of pigs which had not been given antibiotics. It is concluded that antibiotic treatment of farm animals may lead to acquisition of antibiotic resistance by gut coliforms of man.
对来自猪及其人类接触者粪便样本中的大肠菌群的抗生素耐药模式进行了研究。检测了耐药大肠菌群在体外将其耐药性转移至抗生素敏感受体的能力。结果表明，接受过抗生素治疗的猪携带的多重耐药、带有R因子的大肠菌群比未接受抗生素治疗的猪更多。接受过抗生素治疗的猪的人类接触者中，带有R因子的抗生素耐药大肠菌群的发生率高于未接受抗生素治疗的猪的人类接触者。得出的结论是，对农场动物进行抗生素治疗可能会导致人类肠道大肠菌群获得抗生素耐药性。
