处于“无菌”隔离状态患者粪便中的挥发性脂肪酸。
Volatile fatty acids in the faeces of patients in 'germ-free' isolation.
作者信息
Gompertz D, Brooks A P, Gaya H, Spiers A S
出版信息
Gut. 1973 Mar;14(3):183-6. doi: 10.1136/gut.14.3.183.
Abstract
Faecal volatile fatty acids represent the end products of the metabolism of the anaerobic flora of the large bowel. The excretion of these volatile acids has been investigated in five leukaemic patients maintained in plastic ;germ-free' isolators. Under ;isolator' conditions there is a pronounced fall in volatile fatty acid excretion. The possibility that the measurement of these acids may be used to monitor anaerobic overgrowth and recolonization in these patients is discussed.
摘要
粪便挥发性脂肪酸是大肠厌氧菌群代谢的终产物。对五名在塑料“无菌”隔离器中维持治疗的白血病患者的这些挥发性酸的排泄情况进行了研究。在“隔离器”条件下，挥发性脂肪酸排泄量显著下降。文中讨论了测定这些酸可用于监测这些患者厌氧菌群过度生长和重新定植的可能性。
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本文引用的文献
1
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Proc Soc Exp Biol Med. 1964 Oct;117:97-100. doi: 10.3181/00379727-117-29505.
2
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Appl Microbiol. 1957 Nov;5(6):406-12. doi: 10.1128/am.5.6.406-412.1957.
3
Metabolic effects of oral neomycin.口服新霉素的代谢效应。
Clin Sci. 1967 Aug;33(1):111-24.
4
In vivo dialysis of faeces as a method of stool analysis. IV. The organic anion component.粪便的体内透析作为一种粪便分析方法。IV. 有机阴离子成分。
Clin Sci. 1969 Oct;37(2):549-64.
5
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Gastroenterology. 1971 Jun;60(6):1110-29.
6
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Am J Clin Nutr. 1970 Nov;23(11):1533-40. doi: 10.1093/ajcn/23.11.1533.
7
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J Infect Dis. 1969 Jun;119(6):641-9. doi: 10.1093/infdis/119.6.641.
8
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