停滞袢综合征中的空肠内挥发性脂肪酸
Intrajejunal volatile fatty acids in the stagnant loop syndrome.
作者信息
Chernov A J, Doe W F, Gompertz D
出版信息
Gut. 1972 Feb;13(2):103-6. doi: 10.1136/gut.13.2.103.
Abstract
In the stagnant loop syndrome an abnormal anaerobic flora colonizes the small bowel. Anaerobic organisms are characterized by fermentation reactions leading to the production of volatile fatty acids. This paper describes the measurement of intrajejunal volatile fatty acid concentrations in 11 patients with the stagnant loop syndrome. Nine normal persons and 18 patients with gastrointestinal disease without intestinal stasis acted as controls. Acetate and propionate concentrations were greatly increased in the patients with the stagnant loop syndrome and returned to normal in those patients treated with antibiotics. The measurement of intrajejunal volatile fatty acid concentrations as an index of overgrowth of anaerobic organisms is discussed.
摘要
在淤滞环综合征中，异常的厌氧菌群在小肠定植。厌氧生物的特征是发酵反应，导致挥发性脂肪酸的产生。本文描述了11例淤滞环综合征患者空肠内挥发性脂肪酸浓度的测定。9名正常人和18名无肠道淤滞的胃肠道疾病患者作为对照。淤滞环综合征患者的乙酸盐和丙酸盐浓度大幅升高，而接受抗生素治疗的患者这些浓度恢复正常。本文还讨论了将空肠内挥发性脂肪酸浓度的测定作为厌氧生物过度生长指标的问题。
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