Müller R P, Vosberg H, Peters P E, Hemmelskamp S
Strahlentherapie. 1979 Apr;155(4):243-7.
Between 1974 and March 1977, lymph scintigrams were taken on 68 patients with operated malignant melanomas of the inferior extremity before submitting these patients to an endolymphatic radionuclide therapy. The authors wanted to prove that the lymph canals were undamaged in order to avoid unnecessary cutaneous irradiation damages in case of a subsequent additional therapy. 58 lymph scintigrams showed normal findings with a symmetrical transport of 99mtechnetium-sulfur colloid into the inguinal and iliacal lymph nodes of both sides. The ELRT could be accomplished successfully on all patients of this group. Ten lymph scintigrams showed pathological findings with evidence of activity in the wound region. The ELRT was cancelled in eight cases, and two essays had to be stopped without any success. Our experiences show that lymph scintigraphy with 99mtechnetium-sulfur colloid is a simple and reliable method to examine the lymph canals of the inferior extremities. In case of patholological findings, one can avoid to order unnecessarily the expensive radioactive substance for the endolymphatic radionuclide therapy. An alternative punction point to that on the instep which is ordinarily used can possibly be found by a repeated examination.
1974年至1977年3月期间,在68例下肢恶性黑色素瘤手术患者接受内淋巴放射性核素治疗前,进行了淋巴闪烁扫描。作者想要证明淋巴管未受损,以免在后续附加治疗时造成不必要的皮肤辐射损伤。58例淋巴闪烁扫描结果正常,99m锝-硫胶体对称输送至双侧腹股沟和髂淋巴结。该组所有患者均成功完成了内淋巴放射性核素治疗。10例淋巴闪烁扫描结果异常,伤口区域有活性证据。8例取消了内淋巴放射性核素治疗,2例治疗未成功便不得不中止。我们的经验表明,99m锝-硫胶体淋巴闪烁扫描是检查下肢淋巴管的一种简单可靠的方法。如果结果异常,可避免不必要地订购用于内淋巴放射性核素治疗的昂贵放射性物质。通过重复检查,可能会找到一个不同于通常使用的足背穿刺点的替代穿刺点。