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[下肢内淋巴放射性核素治疗(ELRT)中使用限量造影剂获得的诊断结果的可靠性(作者译)]

[Reliability of the diagnostic results obtained with confined quantities of the contrast medium in endolymphatic radionuclide therapy (ELRT) of the inferior limbs (author's transl)].

作者信息

Müller R P, Schnepper E, Peters P E, Fladerer W

出版信息

Strahlentherapie. 1980 Aug;156(8):538-41.

PMID:7414647
Abstract

Endolymphatic radionuclide therapy (ELRT) produces not only a radiotherapeutic effect on the lymph nodes but makes possible also to judge of the lymph nodes being stained with labelled lipiodol UF. With the purpose of avoiding an eventual radiation exposure of the lung, or at least of confining it to a minimum, only limited quantities not exceeding 3.5 ml (5 mCi of 32P; 0.5 mCi of 131I) of the oily contrast medium for unilateral, or twice 3.5 ml (together 4 mCi of 32P; 0.5 mCi of 131I) for bilateral application. A retrospective analysis of 245 patients of the study group for endolymphatic radionuclide therapy, who suffered from malignant melanomas of the inferior limbs, revealed 77.5% of correct diagnoses. Most of the false-positive findings (44/70) seem to be due to the knowledge of the primary disease, as 77% of these cases had been described as "suspicious". False-negative findings turned out in 5% only. The findings which had been characterized as "surely positive" proved reliable in 90%. The good results of lymphography with smaller quantities of the contrast medium are, on the whole, comparable to those of primary diagnostic lymphography.

摘要

内淋巴放射性核素疗法(ELRT)不仅对淋巴结产生放射治疗效果,还能够判断标记超液态碘化油对淋巴结的染色情况。为避免肺部受到潜在辐射,或至少将其降至最低限度,单侧应用油性造影剂的量限制在不超过3.5毫升(32P为5毫居里;131I为0.5毫居里),双侧应用则为两次3.5毫升(32P共4毫居里;131I为0.5毫居里)。对245例接受内淋巴放射性核素治疗研究组患者进行回顾性分析,这些患者患有下肢恶性黑色素瘤,结果显示正确诊断率为77.5%。大多数假阳性结果(44/70)似乎是由于对原发疾病的了解,因为这些病例中有77%被描述为“可疑”。假阴性结果仅占5%。被判定为“肯定阳性”的结果在90%的情况下被证明是可靠的。总体而言,使用较少量造影剂的淋巴造影的良好结果与初次诊断性淋巴造影的结果相当。

相似文献

1
[Reliability of the diagnostic results obtained with confined quantities of the contrast medium in endolymphatic radionuclide therapy (ELRT) of the inferior limbs (author's transl)].[下肢内淋巴放射性核素治疗(ELRT)中使用限量造影剂获得的诊断结果的可靠性(作者译)]
Strahlentherapie. 1980 Aug;156(8):538-41.
2
[Lymphographically detectable long-term changes caused by endolymphatic radionuclide therapy (ELRT) in the infradiaphragmatic lymph system].[经淋巴管造影检测的膈下淋巴系统内淋巴放射性核素治疗(ELRT)引起的长期变化]
Strahlentherapie. 1985 Apr;161(4):239-43.
3
[Endolymphatic radionuclide therapy of the malignant melanoma (author's transl)].恶性黑色素瘤的内淋巴放射性核素治疗(作者译)
Strahlentherapie. 1978 Mar;154(3):169-73.
4
[Clinical results of endolymphatic radionuclide therapy in the treatment of malignant melanoma].
Strahlentherapie. 1974 Jul;148(1):1-15.
5
[Radiation dose to the lung following endolymphatic radionuclide therapy of melanoma of the lower limbs].
Strahlentherapie. 1985 Jan;161(1):23-9.
6
[Vitality evaluation of malignant melanoma metastases following endolymphatic radionuclide therapy using the Falck-Hillarp method].[使用法尔克-希拉尔普方法对放射性核素内淋巴治疗后恶性黑色素瘤转移灶的活力评估]
Hautarzt. 1975 Jun;26(6):317-20.
7
[Scintigraphic examinations of the lymph before endolymphatic radionuclide therapy of the malignant melanoma of the inferior extremity (author's transl)].下肢恶性黑色素瘤内淋巴放射性核素治疗前的淋巴闪烁造影检查(作者译)
Strahlentherapie. 1979 Apr;155(4):243-7.
8
Distribution pattern of radioactive labelled lipiodol-UF following intralymphatic application for therapy.放射性标记的超液态碘化油经淋巴管内注射用于治疗后的分布模式。
Lymphology. 1976 Sep;9(3):122-6.
9
The application of a digital whole body scanner to the dosimetry of intralymphatic 32P/131I Lipiodol.数字全身扫描仪在淋巴内注射32P/131I碘油剂量测定中的应用。
Br J Radiol. 1976 Sep;49(585):779-87. doi: 10.1259/0007-1285-49-585-779.
10
Current status of endolymphatic therapy with radionuclides.放射性核素内淋巴治疗的现状
Lymphology. 1974 Mar;7(1):49-52.