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利用Qβ复制酶合成异源RNA的互补链。

Synthesis of complementary strands of heterologous RNAs with Qbeta replicase.

作者信息

Palmenberg A, Kaesberg P

出版信息

Proc Natl Acad Sci U S A. 1974 Apr;71(4):1371-5. doi: 10.1073/pnas.71.4.1371.

DOI:10.1073/pnas.71.4.1371
PMID:4524642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388230/
Abstract

Qbeta replicase, in the presence of Mn(++), can use various RNAs as templates for synthesis of full-length RNA products and can also use Qbeta plus-strand RNA as template in the absence of host factors.

摘要

Qβ复制酶在有Mn(++)存在的情况下,能以各种RNA作为模板来合成全长RNA产物,并且在没有宿主因子的情况下也能以Qβ正链RNA作为模板。

相似文献

1
Synthesis of complementary strands of heterologous RNAs with Qbeta replicase.利用Qβ复制酶合成异源RNA的互补链。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1371-5. doi: 10.1073/pnas.71.4.1371.
2
Resynchronization of RNA synthesis by coliphage Qbeta replicase at an internal site of the RNA template.噬菌体Qβ复制酶在RNA模板内部位点对RNA合成的重新同步化。
J Mol Biol. 1973 May 15;76(2):271-84. doi: 10.1016/0022-2836(73)90391-4.
3
Minimal requirements for template recognition by bacteriophage Qbeta replicase: approach to general RNA-dependent RNA synthesis.噬菌体Qβ复制酶识别模板的最低要求:通用RNA依赖RNA合成的方法
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2640-3. doi: 10.1073/pnas.72.7.2640.
4
Submit complex 3-IV as the nucleotide binding site of Q-beta replicase.提交复合物3-IV作为Q-β复制酶的核苷酸结合位点。
Nature. 1974 Jun 14;249(458):659-62. doi: 10.1038/249659a0.
5
Evidence for de novo production of self-replicating and environmentally adapted RNA structures by bacteriophage Qbeta replicase.
Proc Natl Acad Sci U S A. 1975 Jan;72(1):162-6. doi: 10.1073/pnas.72.1.162.
6
Synthesis of probes for RNA using Qbeta-replicase.使用Qβ复制酶合成RNA探针。
Biochem Biophys Res Commun. 1975 May 19;64(2):640-7. doi: 10.1016/0006-291x(75)90369-1.
7
Isolation and properties of RNA replicases induced by SP and FI phages.由SP和FI噬菌体诱导产生的RNA复制酶的分离与特性
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1778-9. doi: 10.1073/pnas.68.8.1778.
8
Initiation of transcription by RNA polymerases of Escherichia coli and phage T3.大肠杆菌和噬菌体T3的RNA聚合酶引发的转录起始
Basic Life Sci. 1974;3:115-23. doi: 10.1007/978-1-4613-4529-9_10.
9
Cell-free protein synthesis resulting in active phage Qbeta replicase.
Nat New Biol. 1973 Oct 3;245(144):141-3. doi: 10.1038/newbio245141a0.
10
Structure and function of RNA replicase of bacteriophage Qbeta.噬菌体Qβ RNA复制酶的结构与功能
Arch Int Physiol Biochim. 1975 Dec;83(5):909-48.

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Q beta replicase template specificity: different templates require different GTP concentrations for initiation.Qβ复制酶模板特异性:不同模板起始需要不同的鸟苷三磷酸(GTP)浓度。
Proc Natl Acad Sci U S A. 1980 May;77(5):2601-5. doi: 10.1073/pnas.77.5.2601.

本文引用的文献

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PHYSICAL AND CHEMICAL PROPERTIES OF RNA FROM THE BACTERIAL VIRUS R17.来自细菌病毒R17的RNA的物理和化学性质
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REPLICATION OF RNA VIRUSES I. CHARACTERIZATION OF A VIRAL RNA-DEPENDENT RNA POLYMERASE.RNA病毒的复制I.病毒RNA依赖性RNA聚合酶的特性
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Purification of viral RNA by means of bentonite.通过膨润土纯化病毒RNA。
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Terminal sequences of bacteriophage RNAs.噬菌体RNA的末端序列。
Nature. 1968 Nov 9;220(5167):548-52. doi: 10.1038/220548a0.
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Specific interaction of tobacco mosaic virus RNA with Q beta-replicase.
Virology. 1971 Jan;43(1):69-74. doi: 10.1016/0042-6822(71)90225-x.
7
Characterization of the subunits of Q-beta replicase.Q-β复制酶亚基的表征
Nature. 1970 Nov 7;228(5271):527-33. doi: 10.1038/228527a0.
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Subunit structure of Q-beta replicase.Q-β复制酶的亚基结构。
Nature. 1970 Nov 7;228(5271):525-7. doi: 10.1038/228525a0.
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Replication of RNA viruses. 8. Direction of chain growth in the Q-beta RNA polymerase reaction.
J Mol Biol. 1969 Mar 28;40(3):445-55. doi: 10.1016/0022-2836(69)90164-8.
10
Recognition of size and sequence by an RNA replicase.RNA复制酶对大小和序列的识别。
Proc Natl Acad Sci U S A. 1965 Oct;54(4):1189-93. doi: 10.1073/pnas.54.4.1189.