参与肌球蛋白和肌红蛋白信使核糖核酸翻译的特定起始因子的分离以及一种参与翻译的新核糖核酸的分离。
Separation of specific initiation factors involved in the translation of myosin and myoglobin messenger RNAs and the isolation of a new RNA involved in translation.
作者信息
Heywood S M, Kennedy D S, Bester A J
出版信息
Proc Natl Acad Sci U S A. 1974 Jun;71(6):2428-31. doi: 10.1073/pnas.71.6.2428.
Abstract
Two messenger specific factors, phosphocellulose fractions 3 and 4, have been isolated from the initiation factor 3 fraction of red muscle initiation factors by chromatography on phosphocellulose. When added to a reticulocyte cell-free system containing both myoglobin and myosin mRNAs, phosphocellulose fraction 3 is found to specifically stimulate the synthesis of myoglobin while phosphocellulose fraction 4 is found to specifically stimulate the synthesis of myosin. In addition, a new RNA, isolated from the initiation factor 3 fraction, is shown to specifically inhibit the translation of heterologous mRNAs.
摘要
通过磷酸纤维素柱层析，从红色肌肉起始因子的起始因子3组分中分离出了两种信使特异性因子，即磷酸纤维素组分3和4。当将磷酸纤维素组分3添加到含有肌红蛋白和肌球蛋白mRNA的网织红细胞无细胞体系中时，发现它能特异性地刺激肌红蛋白的合成；而当将磷酸纤维素组分4添加到该体系中时，则发现它能特异性地刺激肌球蛋白的合成。此外，从起始因子3组分中分离出的一种新RNA，被证明能特异性抑制异源mRNA的翻译。
相似文献
1
Separation of specific initiation factors involved in the translation of myosin and myoglobin messenger RNAs and the isolation of a new RNA involved in translation.参与肌球蛋白和肌红蛋白信使核糖核酸翻译的特定起始因子的分离以及一种参与翻译的新核糖核酸的分离。
Proc Natl Acad Sci U S A. 1974 Jun;71(6):2428-31. doi: 10.1073/pnas.71.6.2428.
2
Messenger RNA affinity column fractionation of eukaryotic initiation factor and the translation of myosin messenger RNA.真核生物起始因子的信使核糖核酸亲和柱分级分离及肌球蛋白信使核糖核酸的翻译
Arch Biochem Biophys. 1979 Jan;192(1):270-81. doi: 10.1016/0003-9861(79)90092-4.
3
4
[Control of protein synthesis during development (author's transl)].
Tanpakushitsu Kakusan Koso. 1976 Feb 1;21(2):81-90.
5
Basic aspects of protein synthesis in muscle.
J Anim Sci. 1974 May;38(5):1050-3. doi: 10.2527/jas1974.3851050x.
6
Translation of myoglobin messenger ribonucleic acid.肌红蛋白信使核糖核酸的翻译
Biochemistry. 1973 Nov 6;12(23):4559-65. doi: 10.1021/bi00747a002.
7
Purification of myosin translational control RNA and its interaction with myosin messenger RNA.肌球蛋白翻译控制RNA的纯化及其与肌球蛋白信使RNA的相互作用。
Biochemistry. 1976 Jul 27;15(15):3314-9. doi: 10.1021/bi00660a023.
8
The role of muscle and reticulocyte initiation factor 3 on the translation of myosin and globin messenger RNA in a wheat germ cell-free system.
FEBS Lett. 1976 Dec 31;72(2):314-8. doi: 10.1016/0014-5793(76)80994-5.
9
Cell-free synthesis of myosin.肌球蛋白的无细胞合成
Methods Enzymol. 1974;30:669-74. doi: 10.1016/0076-6879(74)30064-x.
10
The translation of globin messenger RNA with use of muscle initiation factors.利用肌肉起始因子对珠蛋白信使核糖核酸进行翻译。
Biochim Biophys Acta. 1977 Mar 18;475(2):393-402. doi: 10.1016/0005-2787(77)90028-4.
引用本文的文献
1
Translational regulation of Chk1 expression by eIF3a via interaction with the RNA-binding protein HuR.eIF3a通过与RNA结合蛋白HuR相互作用对Chk1表达进行翻译调控。
Biochem J. 2020 May 29;477(10):1939-1950. doi: 10.1042/BCJ20200025.
2
Blood Circulating miRNAs as Cancer Biomarkers for Diagnosis and Surgical Treatment Response.循环血液中的微小RNA作为癌症诊断和手术治疗反应的生物标志物
Front Genet. 2019 Mar 11;10:169. doi: 10.3389/fgene.2019.00169. eCollection 2019.
3
Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex.真核起始因子 3a 的 spectrin 结构域是 a:b:i:g 亚基复合物形成的对接位点。
J Biol Chem. 2013 Sep 27;288(39):27951-9. doi: 10.1074/jbc.M113.483164. Epub 2013 Aug 6.
4
MicroRNAs: molecular features and role in cancer.微小 RNA：分子特征及其在癌症中的作用。
Front Biosci (Landmark Ed). 2012 Jun 1;17(7):2508-40. doi: 10.2741/4068.
5
In vitro translation studies of the cytoplasmic nonpolysomal particles containing messenger RNA.对含有信使核糖核酸的细胞质非多核糖体颗粒的体外翻译研究。
Nucleic Acids Res. 1980 Apr 25;8(8):1793-804. doi: 10.1093/nar/8.8.1793.
6
Uptake and utilization of mRNA by myogenic cells in culture.培养的成肌细胞对mRNA的摄取和利用。
J Cell Biol. 1980 Oct;87(1):65-71. doi: 10.1083/jcb.87.1.65.
7
Turnover of the creatine kinase subunits in chicken myogenic cell cultures and in fibroblasts.鸡成肌细胞培养物和成纤维细胞中肌酸激酶亚基的周转
Biochem J. 1981 May 15;196(2):377-82. doi: 10.1042/bj1960377.
8
Potential role of mRNP proteins in cytoplasmic control of gene expression in duck erythroblasts.mRNP蛋白在鸭成红细胞基因表达的细胞质控制中的潜在作用。
Mol Biol Rep. 1981 May 22;7(1-3):71-81. doi: 10.1007/BF00778736.
9
Translation of hepatic mRNA in extracts from wheat germ embryos.小麦胚芽提取物中肝脏信使核糖核酸的翻译
Mol Biol Rep. 1974 Dec;1(8):483-91. doi: 10.1007/BF00360676.
10
Posttranscriptional control of embryonic rat skeletal muscle protein synthesis. Control at the level of translation by endogenous RNA.胚胎大鼠骨骼肌蛋白质合成的转录后调控。内源性RNA在翻译水平的调控。
J Cell Biol. 1988 Sep;107(3):1085-98. doi: 10.1083/jcb.107.3.1085.
本文引用的文献
1
Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA.高等生物中特定基因表达的调控。哺乳动物基因的表达可能受作用于信使核糖核酸翻译的阻遏物调控。
Science. 1969 Dec 19;166(3912):1474-80. doi: 10.1126/science.166.3912.1474.
2
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
3
Hemoglobin messenger ribonucleic acid. Distribution of the 9S ribonucleic acid in polysomes of different sizes.血红蛋白信使核糖核酸。9S核糖核酸在不同大小多核糖体中的分布。
Biochemistry. 1969 Mar;8(3):829-31. doi: 10.1021/bi00831a010.
4
Myosin synthesis and specificity of eukaryotic initiation factors.肌球蛋白的合成与真核起始因子的特异性
Biochemistry. 1972 May 23;11(11):2061-6. doi: 10.1021/bi00761a010.
5
Translation of myoglobin messenger ribonucleic acid.肌红蛋白信使核糖核酸的翻译
Biochemistry. 1973 Nov 6;12(23):4559-65. doi: 10.1021/bi00747a002.
6
Regulation of protein synthesis in mammalian cells. V. Further studies on the effect of actinomycin D on translation control in HeLa cells.哺乳动物细胞中蛋白质合成的调控。V. 放线菌素D对HeLa细胞翻译控制影响的进一步研究。
J Mol Biol. 1973 Oct 25;80(2):243-54. doi: 10.1016/0022-2836(73)90170-8.
7
Presence of a new RNA species among the initiation protein factors active in eukaryotes translation.在真核生物翻译中发挥作用的起始蛋白因子中存在一种新的RNA种类。
Biochem Biophys Res Commun. 1973 Sep 5;54(1):25-32. doi: 10.1016/0006-291x(73)90883-8.
8
The effects of inhibitors of RNA and DNA synthesis on protein synthesis and polysome levels in mouse L-cells.RNA和DNA合成抑制剂对小鼠L细胞中蛋白质合成及多核糖体水平的影响。
J Cell Physiol. 1973 Oct;82(2):133-50. doi: 10.1002/jcp.1040820202.
9
Translational control of and globin chain synthesis.
Nat New Biol. 1972 Dec 27;240(104):274-6. doi: 10.1038/newbio240274a0.
10
Discrimination between messenger ribonucleic acids by a mammalian translation initiation factor.哺乳动物翻译起始因子对信使核糖核酸的区分
Proc Natl Acad Sci U S A. 1973 Jul;70(7):2139-44. doi: 10.1073/pnas.70.7.2139.
Zotero 插件