Arvidson B
Acta Neuropathol. 1979 Apr 12;46(1-2):139-44. doi: 10.1007/BF00684815.
The perineurial diffusion barrier to horseradish peroxidase (HRP) and ferritin was investigated in superior cervical ganglia of rats and mice. The ganglion was surrounded by a delicate epineurium and 2-5 perineurial lamellae joined by zonulae occludentes and desmosomes. Following local application of tracers the animals were killed after 5, 30, and 60 min and the distribution of HRP and ferritin was studied by light and electron microscopy. The inner layers of the ganglionic perineurium prevented diffusion of both HRP and ferritin perineurial lamellae investing the ganglion. HRP had often extended to the innermost lamella 60 min after application. HRP and ferritin were present in vesicles of ganglionic perineurial cells. There was no passage of tracers via intercellular junctions.
在大鼠和小鼠的颈上神经节中，研究了神经束膜对辣根过氧化物酶（HRP）和铁蛋白的扩散屏障作用。神经节被一层薄的神经外膜所包围，2至5层神经束膜薄片通过紧密连接和桥粒相连。在局部应用示踪剂后，分别于5分钟、30分钟和60分钟处死动物，并通过光学显微镜和电子显微镜研究HRP和铁蛋白的分布。神经节神经束膜的内层阻止了HRP和铁蛋白在包绕神经节的神经束膜薄片中的扩散。应用HRP 60分钟后，其常常延伸至最内层薄片。HRP和铁蛋白存在于神经节神经束膜细胞的囊泡中。示踪剂不会通过细胞间连接进行传递。
