Gall J G
Proc Natl Acad Sci U S A. 1974 Aug;71(8):3078-81. doi: 10.1073/pnas.71.8.3078.
In the macronucleus of the ciliated protozoan, Tetrahymena pyriformis GL, the genes coding for 17S and 25S rRNA exist as free, extrachromosomal molecules. About 90% of the molecules are linear with a molecular weight of 12.6 x 10(6). Most of the remainder are circles of the same size, or lariats (circles with tails). A few dimers and oligomers are found. The extrachromosomal rDNA of Tetrahymena represents a kind of gene amplification that may be common among primitive eukaryotes.
在梨形四膜虫GL的大核中,编码17S和25S核糖体RNA的基因以游离的、染色体外分子的形式存在。约90%的分子是线性的,分子量为12.6×10⁶。其余大部分是相同大小的环状分子,或套索状结构(带尾巴的环状分子)。还发现了一些二聚体和寡聚体。四膜虫的染色体外核糖体DNA代表了一种基因扩增现象,这在原始真核生物中可能很常见。