Grant V, Flake R H
Proc Natl Acad Sci U S A. 1974 Oct;71(10):3863-5. doi: 10.1073/pnas.71.10.3863.
There are various biologically realistic ways around the cost-of-selection restriction on rapid multiple-gene substitution. Some of these ways depend upon particular forms of interaction or linkage in the genes undergoing substitution; other ways depend on particular conditions of population size and structure. The special genotypic and populational conditions required for rapid evolutionary change in genetically complex characters are not unusual in higher organisms.
对于快速多基因替代中选择成本限制，存在多种生物学上合理的解决方法。其中一些方法取决于正在发生替代的基因的特定相互作用形式或连锁关系；其他方法则取决于种群大小和结构的特定条件。在高等生物中，基因复杂性状快速进化变化所需的特殊基因型和种群条件并非罕见。
